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Cyclohexane-1,2-dione-mono-o-tolylhydrazone is a chemical compound with the molecular formula C13H14N2O. It is a derivative of cyclohexane-1,2-dione, which is a six-membered ring with two carbonyl groups (C=O) at positions 1 and 2. The compound is formed by the addition of an o-tolylhydrazone group to the cyclohexane-1,2-dione molecule. The o-tolylhydrazone group consists of a tolyl (methylphenyl) moiety attached to a hydrazine (NH2) group, which then forms a hydrazone bond with the carbonyl group of the cyclohexane-1,2-dione. This results in a stable, conjugated system that exhibits unique chemical and physical properties. Cyclohexane-1,2-dione-mono-o-tolylhydrazone is often used in organic synthesis and as a ligand in coordination chemistry due to its ability to form stable complexes with various metal ions.

2257-18-3

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2257-18-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2257-18-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,5 and 7 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 2257-18:
(6*2)+(5*2)+(4*5)+(3*7)+(2*1)+(1*8)=73
73 % 10 = 3
So 2257-18-3 is a valid CAS Registry Number.

2257-18-3Downstream Products

2257-18-3Relevant academic research and scientific papers

A novel necroptosis inhibitor - Necrostatin-21 and its SAR study

Wu, Zhijie,Li, Ying,Cai, Yu,Yuan, Junying,Yuan, Chengye

, p. 4903 - 4906 (2013/09/02)

An initial structure-activity relationship study of the novel necroptosis inhibitor Nec-21 was described. Any changes of the tetracyclic scaffold were detrimental for the activity. Introduction of a substituent to 7 or 8 position (e.g., cyano or methoxy group, respectively), would increase the activity. The 7 and 8-position disubstituted compound 17b was 35-fold as potent as the lead, while EC50 reached 14 nM.

Synthesis of 2-hydroxypyrido[2,3-a]carbazoles and 2-hydroxypyrimido[4,5- a]carbazoles from 1-hydroxycarbazoles

Shanmugasundaram, Kandasamy,Rajendra Prasad, Karnam J.

, p. 2163 - 2169 (2007/10/03)

Gattermann reaction on substituted 1-hydroxycarbazoles (4a-d) afforded substituted 1-hydroxycarbazole-2-carbaldehydes (5a-d) from which synthesis of either 2-hydroxypyrido[2,3-a]carbazoles (7a-d) via Perkin reaction or 2- hydroxypyrimido[4,5-a]carbazoles (8a-d) via condensation with urea could be achieved.

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