22577-14-6

Basic information

• Product Name: 2-(2-Propen-1-yloxy)-acetic acid
• Synonyms: 2-(2-Propen-1-yloxy)-acetic acid;2-(Prop-2-en-1-yloxy)acetic acid;2-(allyloxy)acetic acid;Acetic acid, 2-(2-propen-1-yloxy)-
• CAS NO: 22577-14-6
• Molecular Formula: C₅H₈O₃
• Molecular Weight: 116.12
• Mol File: 22577-14-6.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 108-109 °C(Press: 7 Torr)
• Appearance: /
• Density: 1.0965 g/cm3
• PKA: 3.46±0.10(Predicted)
• CAS DataBase Reference: 2-(2-Propen-1-yloxy)-acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Propen-1-yloxy)-acetic acid(22577-14-6)
• EPA Substance Registry System: 2-(2-Propen-1-yloxy)-acetic acid(22577-14-6)

Safety Data

• Hazardous Substances Data: 22577-14-6(Hazardous Substances Data)

Usage

Physical state

It is a colorless liquid.

Odor

The compound has a pungent odor.

Usage in production

It is commonly used in the production of polymers, adhesives, and coatings.

Monomer in synthesis

Allyl acrylate is utilized as a monomer in the synthesis of various polymers, including polyacrylic acid and its derivatives.

Hazardous nature

It is considered to be a hazardous chemical due to its potential to cause skin and eye irritation, as well as its flammability and reactivity.

Safety precautions

Proper safety precautions should be taken when handling and using this compound to avoid potential hazards.

Upstream product

• 20907-32-8 sodium allyloxide 
• 79-11-8 chloroacetic acid 
• 123-34-2 3-allyloxy-1,2-propanediol 
• 85428-58-6 tert-butyl 2-(allyloxy)acetate 
• 3926-62-3 sodium monochloroacetic acid 
• 107-18-6 allyl alcohol 
• 305-53-3 monosodium iodoacetate 
• 79-08-3 bromoacetic acid 
• 15224-07-4 (Allyloxy)essigsaeure-ethylester 

Downstream Products

• 914092-03-8 phenylethyl 3-oxa-5-hexenoate 
• 1120309-29-6 2-(allyloxy)-N-methoxy-N-methylacetamide 
• 197721-28-1 (4S)-3-(2-allyloxyethanoyl)-4-benzyloxazolidin-2-one 

Relevant articles and documents

Tandem Glycolate Claisen Rearrangement/Ring-Closing Metathesis: A Stereochemically General Synthesis of Substituted Dihydropyran-2-carboxylates

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PIPERIDINYL-METHYL-PURINEAMINES AS NSD2 INHIBITORS AND ANTI-CANCER AGENTS

The present invention provides a compound of Formula (I): (I) or an enantiomer, an enantiomeric mixture, or a pharmaceutically acceptable salt thereof; wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds; and methods of using such compounds for treating a disease or condition mediated by nuclear SET domain-containing protein 2 (NSD2).

Silver(I)-Catalyzed Widely Applicable Aerobic 1,2-Diol Oxidative Cleavage

The oxidative cleavage of 1,2-diols is a fundamental organic transformation. The stoichiometric oxidants that are still predominantly used for such oxidative cleavage, such as H5IO6, Pb(OAc)4, and KMnO4, generate stoichiometric hazardous waste. Herein, we describe a widely applicable and highly selective silver(I)-catalyzed oxidative cleavage of 1,2-diols that consumes atmospheric oxygen as the sole oxidant, thus serving as a potentially greener alternative to the classical transformations.

METABOLICALLY ROBUST ANALOGS OF CYP-EICOSANOIDS FOR THE TREATMENT OF CARDIAC DISEASE

The present invention relates to compounds according to general formula (I) which are metabolically robust analogues of bioactive lipid mediators derived from omega-3 polyunsaturated fatty acids (n-3 PUFAs).The present invention further relates to composi