2258-92-6Relevant articles and documents
Preparation method of trans-1, 3-diolefine
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Paragraph 0068; 0070, (2021/03/18)
The invention discloses a preparation method of trans-1, 3-diolefine, which comprises the following step: under the action of 4-dimethylaminopyridine and triethylamine, reacting 2, 3-dihydroxy propyl(9E, 12E)-9, 12-octadecadienoic acid ester with (9E, 12E)-9, 12-octadecadienoyl chloride to obtain the trans-1, 3-diolefine. Compared with the prior art, the method disclosed by the invention is simpleto operate, high in reaction selectivity and high in product yield.
Preparation method of linolenic acid glyceride
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Paragraph 0015; 0016; 0017, (2017/07/04)
The invention relates to the field of chemical synthesis, in particular to a preparation method of linolenic acid glyceride. The preparation method of the linolenic acid glyceride comprises the steps that low sodium alcoholate or low potassium alcoholate is used as a catalyst, low fatty acid alcohol ester and glycerol are blended according to the mole ratio of 2:1 and react for 10-20 h at 100-170 DEG C under a vacuum condition so as to obtain a crude glyceride product; and the crude glyceride product is subjected to subsequent processing and treatment, and a corresponding product is prepared. By adoption of the preparation method under a solvent-free system, a remarkable effect is achieved on improving of the productivity and the quality, and the content of linolenic acid monoester in products is high.
Influence of fatty acid desaturation on spontaneous acyl migration in 2-monoacylglycerols
Compton, David L.,Laszlo, Joseph A.,Appell, Michael,Vermillion, Karl E.,Evans, Kervin O.
, p. 2259 - 2267 (2013/01/15)
The effect of desaturation from the C9 to the C15 carbon of 2-monoacylglycerol (2-MAG) fatty acids on spontaneous acyl migration is described. Three 2-MAG species, 2-monooleoylglycerol (C18:1 cis-Δ9), 2-monolinoleoylglycerol (C18:2 cis-Δ9,12), and 2-monolinolenoylglycerol (C18:3 cis-Δ9,12,15) were synthesized by lipase-catalyzed ethanolysis of their respective triacylglycerols and isolated in >60 % yield and at 2-MAG purities of >95 % relative to 1-monoacylglycerol (1-MAG). 1H-NMR spectroscopy was used to monitor the spontaneous acyl migration of the 2-MAG species over a temperature range from 20 to 80 °C. The relative energies of activation calculated from the Arrhenius relationships of the 2-MAG acyl migration rate constants were 73.3, 68.0, and 72.9 kJ mol-1 for the three 2-MAG species, respectively. Density functional calculations performed using the B3LYP functional at the 6-31+G* basis set on the three ketal ring intermediate of the three 2-MAG species followed a similar trend with a lack of relative energetic preference associated with the degree of desaturation. The kinetically determined relative activation energies were approximately twofold higher than the theoretical relative Gibbs free energies of the intermediates, suggesting that other factors influence acyl migration. In general, increasing desaturation after the C9 carbon of 2-MAG fatty acids had no appreciable effect on acyl migration rates. AOCS (outside the USA) 2012.
