22581-06-2

Basic information

• Product Name: 3-Chloro-4,6-dihydroxy-2-methyl-5-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]benzaldehyde
• Synonyms: 3-Chloro-4,6-dihydroxy-2-methyl-5-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]benzaldehyde;Ilicicolin A
• CAS NO: 22581-06-2
• Molecular Formula: C₂₃H₃₁ClO₃
• Molecular Weight: 0
• Mol File: 22581-06-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 532.1°C at 760 mmHg
• Flash Point: 275.6°C
• Appearance: /
• Density: 1.104g/cm³
• Vapor Pressure: 6.15E-12mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: 3-Chloro-4,6-dihydroxy-2-methyl-5-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-4,6-dihydroxy-2-methyl-5-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]benzaldehyde(22581-06-2)
• EPA Substance Registry System: 3-Chloro-4,6-dihydroxy-2-methyl-5-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]benzaldehyde(22581-06-2)

Safety Data

• Hazardous Substances Data: 22581-06-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C23H31ClO3/c1-15(2)8-6-9-16(3)10-7-11-17(4)12-13-19-22(26)20(14-25)18(5)21(24)23(19)27/h8,10,12,14,26-27H,6-7,9,11,13H2,1-5H3/b16-10+,17-12+

Upstream product

• 94286-85-8 4-chloro-2-farnesylorcinol 
• 122-51-0 orthoformic acid triethyl ester 
• 94286-84-7 4,6-dichloro-2-farnesyl-5-methyl-1,3-cyclohexanedione 
• 94286-83-6 6-farnesyl-1,5-dimethoxy-3-methyl-1,4-cyclohexadiene 
• 24163-93-7 farnesyl bromide 

Relevant articles and documents

DIHYDROOROTIC ACID DEHYDROGENASE INHIBITOR

The present invention provides a novel dihydroorotic acid dehydrogenase inhibitor which is applicable to various diseases. When used as an active ingredient, a compound represented by formula (I): (wherein X represents a halogen atom, R1 represents a hydrogen atom, R2 represents an alkyl group containing 1 to 7 carbon atoms, R3 represents -CHO, and R4 represents -CH2-CH=C(CH3)-R0 (wherein R0 represents an alkyl group containing 1 to 12 carbon atoms which may have a substituent on the terminal carbon and/or on a non-terminal carbon, etc.)), an optical isomer thereof or a pharmaceutically acceptable salt thereof has a high inhibitory effect on dihydroorotic acid dehydrogenase and can be used as an immunosuppressive agent, a therapeutic agent for rheumatism, an anticancer agent, a therapeutic agent for graft rejection, an antiviral agent, an anti-H. pylori agent, a therapeutic agent for diabetes or the like.

SYNTHESIS OF (+/-)-ASCOCHLORIN, (+/-)-ASCOFURANONE AND LL-Z1272α

Three antibiotics with a common structural feature as prenylated phenols were synthesized: (+/-)-ascochlorin (5-chloro-2,4-dihydroxy-6-methyl-3-benzaldehyde), (+/-)-ascofurano