225937-10-0

Basic information

• Product Name: (+)-CATECHIN HYDRATE
• Synonyms: (+)-3,3',4',5,7-FLAVANPENTOL HYDRATE;(+)-3,3',4',5,7-FLAVANPENTOL MONOHYDRATE;3,3',4',5,7-PENTAHYDROXYFLAVANE HYDRATE;(2R,3S)-2-(3,4-DIHYDROXYPHENYL)-3,4-DIHYDRO-1(2H)-BENZOPYRAN-3,5,7-TRIOL;(2R,3S)-2-(3,4-DIHYDROXYPHENYL)-3,4-DIHYDRO-1(2H)-BENZOPYRAN-3,5,7-TRIOL HYDRATE;2R-(3,4-DIHYDROXYPHENYL)-3,4-DIHYDRO-2H-1-BENZOPYRAN-3S,5,7-TRIOL, MONOHYDRATE;CATECHUIC ACID (HYDRATE);CATECHOL (FLAVAN), HYDRATE
• CAS NO: 225937-10-0
• Molecular Formula: C15H16O7
• Molecular Weight: 308.28
• EINECS: 230-731-2
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors
• Mol File: 225937-10-0.mol

Chemical Properties

• Melting Point: 175-177 °C (anhydrous)(lit.)
• Boiling Point: 630.4 °C at760mmHg
• Flash Point: 335 °C
• Appearance: yellow to yellow with tan cast/
• Vapor Pressure: 9.29E-17mmHg at 25°C
• Storage Temp.: 2-8°C
• Solubility: ethanol: soluble50mg/mL
• Merck: 13,1912
• BRN: 3595244
• CAS DataBase Reference: (+)-CATECHIN HYDRATE(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-CATECHIN HYDRATE(225937-10-0)
• EPA Substance Registry System: (+)-CATECHIN HYDRATE(225937-10-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 8-10-23
• Hazardous Substances Data: 225937-10-0(Hazardous Substances Data)

Usage

Uses

Used in Chemical Industry:
(+)-Catechin hydrate is used as an inhibitor of steel corrosion in hydrochloric acid solution for its ability to prevent the corrosion process and protect steel from damage.
Used in Pharmaceutical Research:
(+)-Catechin hydrate is used as a model compound in the study of antimicrobial activities of flavonoids on Escherichia coli, helping researchers understand the potential of these compounds in fighting bacterial infections.
Used in Synthesis:
(+)-Catechin hydrate is used as a starting material for the synthesis of catechin glucosides of biological importance, which can be further utilized in various pharmaceutical and health-related applications.
Used in Wine Industry:
(+)-Catechin hydrate is used as a polyphenol standard in the determination of total polyphenols in the by-products of red wine, allowing for accurate measurement and assessment of the antioxidant content in these by-products.
Used in Animal Nutrition Research:
(+)-Catechin hydrate is used as an additive to study its effects on in vitro methane production and substrate degradation in a triple-fed batch approach, providing insights into its potential role in improving animal feed efficiency and reducing methane emissions.
Used in Microbiology:
(+)-Catechin hydrate is used as a substrate to determine the activity of pure L. plantarum CECT 748T 14 recombinant tannase on catechin, aiding in the understanding of enzyme-catalyzed reactions and their applications in biotechnology and food processing.

Biochem/physiol Actions

An antioxidant flavonoid of plant origin; a free radical scavenger, preventing free radical-mediated damage in a variety of biological systems. For example, at physiological pH catechin suppressed DNA strand breaks by hydroxyl radicals. It has also been shown to prevent human plasma oxidation. It delayed the consumption of endogenous lipid-soluble antioxidants and inhibited lipid oxidation. Catechin may also function as an inhibitor of fatty acid synthase.

InChI:InChI=1/C15H14O6.H2O/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7;/h1-5,13,15-20H,6H2;1H2/t13-,15+;/m0./s1