225943-16-8

Basic information

• Product Name: N-(4-chlorophenyl)-3-phenyl-2-propenethioamide
• Synonyms: N-(4-chlorophenyl)-3-phenyl-2-propenethioamide
• CAS NO: 225943-16-8
• Molecular Formula: C15H12ClNS
• Molecular Weight: 273.78048
• Mol File: 225943-16-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-chlorophenyl)-3-phenyl-2-propenethioamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-chlorophenyl)-3-phenyl-2-propenethioamide(225943-16-8)
• EPA Substance Registry System: N-(4-chlorophenyl)-3-phenyl-2-propenethioamide(225943-16-8)

Safety Data

• Hazardous Substances Data: 225943-16-8(Hazardous Substances Data)

Relevant articles and documents

Thionation of ω-hydroxy amides with Lawesson's reagent: Synthesis of thioenamides and sulfur-containing heterocycles

The thionation of ω-hydroxy amides with Lawesson's reagent [LR: 2,4- bis(p-methoxyphenyl)-1,3,2,4-dithiaphosphetane-2,4-disulfide] is described. The treatment of 3-hydroxy amides 1 with LR exclusively gave thioenamides 2 in fair yields. The treatment of 4-hydroxy amides 5 with LR yielded sulfur- containing heterocycles such as tetrahydrothiophene-2-imines 6 and tetrahydrothiophene-2-thione 7a through cyclization of intermediates, 4- mercapto amides 8. The 5-hydroxy amides 13 also reacted with LR to afford tetrahydrothiopyrane-2-thione 14 as the the sole product.