2260-01-7Relevant academic research and scientific papers
Microbial transformation of epiandrosterone by Aspergillus sydowii
Yildirim, Kudret,Kuru, Ali
, p. 718 - 721 (2016/12/30)
Incubation of epiandrosterone with Aspergillus sydowii MRC 200653 afforded ten metabolites. The fungal dehydrogenation of epiandrosterone is reported for the first time. The formation of the major metabolite, 6?-hydroxyandrost-4-ene-3,17-dione, involved first dehydrogenation to give a 4-ene and then hydroxylation at C-6?. Small amounts of the substrate were hydroxylated at C-1α, C-7α, C-7β and C-11α.
