22606-96-8Relevant academic research and scientific papers
Flash Vacuum Thermolysis of Four Membered Rings Containing Nitrogen Atom. Part IV. Some Mechanistic Aspects of the Thermal Decomposition of Azetidines
Lesniak, S.
, p. 1484 - 1489 (2007/10/03)
Thermal cycloreversions of substituted azetidine rings under FVT conditions have been studied.It was found that the regiochemistry of these reactions depends on the nature of substituents present in the system.The assumed 1,4-diradical stepwise mechanism enabled us to compare the competition in breaking of the first bond (N-C2 or C2-C3) depending on the stability of newly formed 1,4-diradical. - Keywords: azetidines, flash vacuum thermolysis
Reduction of N-Substituted Azetidin-2-ones to Azetidines
Jackson, Mervyn B.,Mander, Lewis N.,Spotswood, Thomas M.
, p. 779 - 788 (2007/10/02)
Reduction of N-substituted azetidin-2-ones to N-substituted azetidines was accomplished rapidly and in good yield with diborane in tetrahydrofuran and with alane in ether.The stereochemistry of the ring substituents was retained under the reaction conditi
