226064-76-2

Upstream product

• 108-24-7 acetic anhydride 
• 226064-62-6 Allyl 4,6-O-benzylidene-3-O-methyl-β-D-glucopyranoside 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 3370-81-8 3-O-methyl-D-glucopyranose 

Downstream Products

• 202647-51-6 2,6-Di-O-benzyl-4-O-levulinyl-3-O-methyl-α-D-glucopyranosyl-(1->4)-2-O-acetyl-6-O-benzyl-3-O-methyl-α-D-glucopyranose trichloroacetimidate 
• 202647-47-0 Prop-1'-enyl 2,6-di-O-benzyl-4-O-levulinyl-3-O-methyl-α-D-glucopyranosyl-(1->4)-2-O-acetyl-6-O-benzyl-3-O-methyl-β-D-glucopyranoside 
• 202647-45-8 Allyl (2,6-di-O-benzyl-4-O-levulinyl-3-O-methyl-α-D-glucopyranosyl)-(1->4)-2-O-acetyl-6-O-benzyl-3-O-methyl-β-D-glucopyranoside 
• 202647-53-8 Allyl 2,6-di-O-benzyl-3-O-methyl-α-D-glucopyranosyl-(1->4)-2-O-acetyl-6-O-benzyl-3-O-methyl-β-D-glucopyranoside 
• 202647-43-6 Allyl 2-O-acetyl-6-O-benzyl-3-O-methyl-β-D-glucopyranoside 

Relevant academic research and scientific papers

Synthetic polysaccharides, preparation method therefor and pharmaceutical compositions containing same

A synthetic polysaccharide including an antithrombin III binding domain consisting of a concatenation of five monosaccharides supporting a total of two carboxylic acid functions and at least four sulpho groups, said domain being directly bound at the non-

Experimental proof for the structure of a thrombin-inhibiting heparin molecule

Kinetic studies of thrombin inhibition by antithrombin in the presence of heparin have shown that thrombin binds to heparin in a preformed heparin-antithrombin complex. To study the relative position of the thrombin binding domain and the antithrombin bin

New synthetic heparin mimetics able to inhibit thrombin and factor Xa

Synthetic pentadeca-, heptadeca- and nonadecasaccharides, comprising an antithrombin III (AT HI) binding pentasaccharide prolonged at the non- reducing end by a thrombin binding domain have been obtained. The pentadecasaccharide is the shortest oligosaccharide able to catalyse thrombin inhibition by AT III. The nonadecasaccharide is a more potent thrombin inhibitor than standard heparin.