226065-30-1Relevant articles and documents
CuI/4-hydro-L-proline as a more effective catalytic system for coupling of aryl bromides with N-boc hydrazine and aqueous ammonia
Jiang, Liqin,Lu, Xu,Zhang, Hui,Jiang, Yongwen,Ma, Dawei
experimental part, p. 4542 - 4546 (2009/09/25)
(Chemical Equation Presented) CuI/4-hydroxy-L-proline-catalyzed coupling of aryl bromides and N-Boc hydrazine takes place in DMSO at 80°C to give N-aryl hydrazides. When aryl iodides are employed, this reaction completes at 50°C and no ligand is required. Under the catalysis of CuI/4-hydroxy-L- proline, the coupling reaction of aqueous ammonia with aryl bromides proceeds smoothly at 50°C to afford primary arylamines. In this case K 2CO3 is found as a better base than Cs2CO 3. These processes allow assembly of N-aryl hydrazides and primary arylamines that bear a wide range of functional groups including hydroxyl, amine, trifluoromethyl, ester, nitro, and ketone.
Photoswitchable unsymmetrical ligand for DNA hetero-mismatches
Dohno, Chikara,Yamamoto, Tsuyoshi,Nakatani, Kazuhiko
scheme or table, p. 4051 - 4058 (2009/12/26)
Photoswitchable DNA-binding ligands should be useful for controlling diverse biological functions involving DNA and reversible assembly of DNA-based nanostructures. In work directed towards the development of photoswitchable ligands with various sequence
Regioselective synthesis of aryl hydrazides by palladium-catalyzed coupling of t-butylcarbazate with substituted aryl bromides
Wang, Zhongren,Skerlj, Renato T.,Bridger, Gary J.
, p. 3543 - 3546 (2007/10/03)
Substituted aryl bromides are coupled with t-butylcarbazate in the presence of a palladium catalyst and base to afford regioselectively, the corresponding amidation product or amination product depending upon the position of the substituents on the aryl b
