22612-65-3

Basic information

• Product Name: (1-hydroxycyclopentyl)(p-tolyl)methanone
• CAS NO: 22612-65-3
• Molecular Weight: 204.269
• Mol File: 22612-65-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1-hydroxycyclopentyl)(p-tolyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (1-hydroxycyclopentyl)(p-tolyl)methanone(22612-65-3)
• EPA Substance Registry System: (1-hydroxycyclopentyl)(p-tolyl)methanone(22612-65-3)

Safety Data

• Hazardous Substances Data: 22612-65-3(Hazardous Substances Data)

Upstream product

• 37802-93-0 1-tetrahydropyran-2-yloxy-cyclopentanecarbonitrile 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 104-85-8 para-methylbenzonitrile 
• 97802-97-6 cyclopentyl(p-tolyl)methanone 
• 6758-17-4 <α-Brom-cyclopentyl>-p-tolyl-keton 

Downstream Products

• 22612-58-4 1-<1-Hydroxy-1-p-tolyl-ethyl>-cyclopentanol-(1) 

Relevant articles and documents

Catalytic Asymmetric Acyloin Rearrangements of α-Ketols, α-Hydroxy Aldehydes, and α-Iminols by N, N′-Dioxide-Metal Complexes

A highly enantioselective acyloin rearrangement of cyclic α-ketols has been developed with a chiral Al(III)-N,N′-dioxide complex as catalyst. This strategy provided an array of optically active 2-acyl-2-hydroxy cyclohexanones in moderate to good yields with high enantioselectivities. The asymmetric isomerizations of acyclic α-hydroxy aldehydes and α-iminols were achieved as well under modified conditions, affording the corresponding chiral α-hydroxy ketones and α-amino ketones in moderate results. Moreover, further transformations of product to enantioenriched diols were carried out.