22634-92-0

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 39, p. 259, 1974 DOI: 10.1021/jo00916a037

InChI:InChI=1/C9H14O5/c1-13-8(11)5-3-7(10)4-6-9(12)14-2/h3-6H2,1-2H3

Upstream product

• 201230-82-2 carbon monoxide 
• 292638-85-8 acrylic acid methyl ester 
• 622-11-7 α-nitroformaldehyde phenylhydrazone 

Downstream Products

• 15889-98-2 (+/-)-methyl γ-butyrolactone-γ-propionate 
• 126135-44-2 Dimethyl γ-hydroxypimelate 
• 333998-04-2 cis-4,5-dibenzyloxycycloheptanone 
• 333998-03-1 cis-8,9-dibenzyloxy-1,4-dioxaspiro[4.6]undecane 
• 99272-65-8 4-[(2R,3R,4R,5R)-2-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-4-[(2-chloro-phenoxy)-hydroxy-phosphoryloxy]-5-(9-phenyl-9H-xanthen-9-yloxymethyl)-tetrahydro-furan-3-yloxy]-4-methoxy-heptanedioic acid dimethyl ester; compound with triethyl-amine 
• 99272-63-6 4-[(2R,3R,4R,5R)-2-(3-Benzoyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-[(2-chloro-phenoxy)-hydroxy-phosphoryloxy]-5-(9-phenyl-9H-xanthen-9-yloxymethyl)-tetrahydro-furan-3-yloxy]-4-methoxy-heptanedioic acid dimethyl ester; compound with triethyl-amine 
• 99272-53-4 4-[(2R,3R,4R,5R)-2-(3-Benzoyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-3-yloxy]-4-methoxy-heptanedioic acid dimethyl ester 
• 99272-54-5 4-[(2R,3R,4R,5R)-2-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-3-yloxy]-4-methoxy-heptanedioic acid dimethyl ester 
• 99272-55-6 2'-O-(3-methoxy-1,5-dicarbomethoxypentanyl)-6-N-benzoyladenosine 
• 99272-56-7 4-{(2R,3R,4R,5R)-2-[2-(4-tert-Butyl-benzoylamino)-6-oxo-1,6-dihydro-purin-9-yl]-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-3-yloxy}-4-methoxy-heptanedioic acid dimethyl ester 
• 99272-58-9 4-[(2R,3R,4R,5R)-2-(3-Benzoyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-hydroxy-5-(9-phenyl-9H-xanthen-9-yloxymethyl)-tetrahydro-furan-3-yloxy]-4-methoxy-heptanedioic acid dimethyl ester 
• 99272-59-0 4-[(2R,3R,4R,5R)-2-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-4-hydroxy-5-(9-phenyl-9H-xanthen-9-yloxymethyl)-tetrahydro-furan-3-yloxy]-4-methoxy-heptanedioic acid dimethyl ester 
• 99272-74-9 4-{(2R,3R,4R,5R)-2-(3-Benzoyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-[(2-chloro-phenoxy)-(9H-fluoren-9-ylmethoxy)-phosphoryloxy]-5-hydroxymethyl-tetrahydro-furan-3-yloxy}-4-methoxy-heptanedioic acid dimethyl ester 
• 99272-75-0 4-{(2R,3R,4R,5R)-2-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-4-[(2-chloro-phenoxy)-(9H-fluoren-9-ylmethoxy)-phosphoryloxy]-5-hydroxymethyl-tetrahydro-furan-3-yloxy}-4-methoxy-heptanedioic acid dimethyl ester 

Relevant academic research and scientific papers

[2]Catenane Synthesis via Covalent Templating

After earlier unsuccessful attempts, this work reports the application of covalent templating for the synthesis of mechanically interlocked molecules (MiMs) bearing no supramolecular recognition sites. Two linear strands were covalently connected in a perpendicular fashion by a central ketal linkage. After subsequent attachment of the first strand to a template via temporary benzylic linkages, the second was linked to the template in a backfolding macrocyclization. The resulting pseudo[1]rotaxane structure was successfully converted to a [2]catenane via a second macrocyclization and cleavage of the ketal and temporary linkages.

1,3-Dipolar Cycloadditions, 87. Contributions to the Chemistry of N-Phenylnitrilimine

The N-phenyl derivative 7 is introduced as the first monosubstituted and interceptible nitrilimine whereas the cycloadditions of disubstituted representatives have been preparatively utilized in the past.Photolysis of 2-phenyltetrazole in the presence of methyl acrylate gives rise to methyl 1-phenyl-2-pyrazoline-5-carboxylate which on further irradiation suffers ring cleavage.The sodium salt of α-nitroformaldehyde phenylhydrazone (15) eliminates NaNO2 in refluxing acetonitrile whereby the intermediate 7 is accepted in situ by acrylic ester, styrene and norbornene.The interaction of methyl acrylate with the anionic precursor 15 furnishes further products.The formal dimer of 7, the 1,4-diphenyl-1,4-dihydro-1,2,4,5-tetrazine, is probably formed by reaction of 7 with 15.

Applications of Homogeneous Water-gas Shift Reaction. IV. Hydrocarbonylation and Dimerization of Methyl Acrylate with CO and H2O

Hydrocarbonylation of methyl acrylate with CO and H2O forms dimethyl 4-oxopimelate in 94percent yield based on H2O, the Co2(CO)8-1,2-bis(diphenylphosphino)ethane (diphos) catalyst system being used as in the case of ethylene or propylene.Increasing temperature tends to promote the dimerization and/or hydrodimerization of methyl acrylate to give 1,3-bis(methoxycarbonyl)-1-butene and/or dimethyl-2-methylglutarate.Effects of CO pressure and H2O concentration on the hydrocarbonylation and dimerization were examined at 135 and 165 deg C.Catalytically active intermediates for the hydrocarbonylation take part in the dimerization of methyl acrylate.