226417-07-8Relevant academic research and scientific papers
The first case of asymmetric induction in intramolecular nitrile imine cycloadditions: Synthesis of enantiopure 3-substituted 6-oxo-2,3,3a,5- tetrahydro-4-carbomethoxy-furo[3,4-c]pyrazoles
Broggini, Gianluigi,Garanti, Luisa,Molteni, Giorgio,Zecchi, Gaetano
, p. 487 - 492 (2007/10/03)
Intramolecular cycloaddition of homochiral nitrile imines 5, generated in situ from base treatment of the corresponding hydrazonoyl chlorides 4, involves diastereoselective formation of the title compounds in the enantiomerically pure form.
