22649-37-2Relevant articles and documents
SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES
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Page/Page column 36-37, (2010/02/16)
The present invention relates to polysubstituted imidazolone derivatives, to the pharmaceutical compositions comprising them and to the therapeutic uses thereof in the human and animal health fields. The present invention also relates to a process for preparing these derivatives.
Wang-aldehyde resin as a recyclable support for the synthesis of α,α-disubstituted amino acid derivatives
Guino, Meritxell,Hii, King Kuok
, p. 3188 - 3193 (2007/10/03)
Merrifield resin was functionalised with hydroxybenzaldehyde under microwave irradiation. The resultant resin was used as a means for immobilisation and activation of α-amino acid esters for alkylation reactions. α,α-Disubstituted and cyclic amino acid esters were prepared in good yields. The Royal Society of Chemistry 2005.
Composition for the treatment of damaged tissue
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, (2008/06/13)
A pharmaceutical for use in damaged tissue, such as wound, treatment (e.g. healing) is described. The pharmaceutical comprising a composition which comprises: (a) a growth factor; and (b) an inhibitor agent; and optionally (c) a pharmaceutically acceptable carrier, diluent or excipient; wherein the inhibitor agent can inhibit the action of at least one specific adverse protein (e.g. a specific protease) that is upregulated in a damaged tissue, such as a wound, environment.