2265-38-5 Usage
Uses
Used in Organic Synthesis:
2,4,6-Tris[3-(trifluoromethyl)phenyl]boroxin is used as a reagent in organic synthesis for its ability to participate in cross-coupling reactions and other transformations involving arylboronic acids. Its unique boron structure contributes to the efficiency and selectivity of these reactions.
Used in Catalytic Processes:
In the field of catalysis, 2,4,6-Tris[3-(trifluoromethyl)phenyl]boroxin serves as a ligand, enhancing the performance of catalytic systems. Its properties allow for improved control over reaction pathways and increased reaction rates.
Used in Pharmaceutical and Agrochemical Synthesis:
2,4,6-Tris[3-(trifluoromethyl)phenyl]boroxin is utilized as a building block in the synthesis of pharmaceuticals and agrochemicals. Its structural features make it a valuable component in the development of new and effective compounds for medical and agricultural applications.
Used in Suzuki-Miyaura Coupling:
Specifically in cross-coupling reactions, 2,4,6-Tris[3-(trifluoromethyl)phenyl]boroxin is used in the Suzuki-Miyaura coupling process, a widely used method for the formation of carbon-carbon bonds, particularly in the synthesis of biaryl compounds.
These applications highlight the versatility and importance of 2,4,6-Tris[3-(trifluoromethyl)phenyl]boroxin in modern organic chemistry and its contribution to the advancement of various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 2265-38-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,6 and 5 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 2265-38:
(6*2)+(5*2)+(4*6)+(3*5)+(2*3)+(1*8)=75
75 % 10 = 5
So 2265-38-5 is a valid CAS Registry Number.
InChI:InChI=1/C21H12B3F9O3/c25-19(26,27)13-4-1-7-16(10-13)22-34-23(17-8-2-5-14(11-17)20(28,29)30)36-24(35-22)18-9-3-6-15(12-18)21(31,32)33/h1-12H
2265-38-5Relevant academic research and scientific papers
Palladium(II)-Catalyzed Enantioselective Synthesis of α-(Trifluoromethyl)arylmethylamines
Johnson, Thomas,Luo, Bo,Lautens, Mark
, p. 4923 - 4930 (2016/07/06)
We describe a method for the synthesis of α-(trifluoromethyl)arylmethylamines that consists of the palladium(II)-catalyzed addition of arylboroxines to imines derived from trifluoroacetaldehyde. Palladium acetate is used as a catalyst with electron-neutral or electron-rich arylboroxines, and it was found that addition of an ammonium or silver salt was crucial to promote the reaction of electron-poor boroxines. With (S)-t-Bu-PyOX as the chiral ligand, this method delivers a variety of α-trifluoromethylated amines in 57-91% yield and with greater than 92% ee in most cases.
Programmed selective sp2 C-O bond activation toward multiarylated benzenes
Zhao, Fei,Zhang, Yun-Fei,Wen, Jing,Yu, Da-Gang,Wei, Jiang-Bo,Xi, Zhenfeng,Shi, Zhang-Jie
supporting information, p. 3230 - 3233 (2013/07/26)
A variety of important multiarylated benzenes were efficiently synthesized from phloroglucinol derivatives 1 through sequential cross-couplings via Pd-catalyzed C-OTs, Ni-catalyzed C-OC(O)NEt2, and C-OMe bond activation. High selectivity was achieved based on the rational design and inherent diversity in the reactivity of different C-O bonds.
Nickel-catalyzed efficient and practical Suzuki-Miyaura coupling of alkenyl and aryl carbamates with aryl boroxines
Xu, Li,Li, Bi-Jie,Wu, Zhen-Hua,Lu, Xing-Yu,Guan, Bing-Tao,Wang, Bi-Qin,Zhao, Ke-Qing,Shi, Zhang-Jie
supporting information; experimental part, p. 884 - 887 (2010/04/29)
(Figure Presented) Suzuki-Miyaura coupling of unactivated alkenyl carbamates Is described to construct polysubstituted olefins. The developed process is also suitable for heteroaromatic and even electron-rich aromatic carbamates.
