226545-65-9Relevant articles and documents
Synthesis of cancer peptide antigen-lipid A analog conjugates for synthetic vaccines
Ikeda, Kiyoshi,Miyajima, Keisuke,Maruyama, Yasufumi,Achiwa, Kazuo
, p. 563 - 568 (2007/10/03)
Conjugates 6 and 7 of cancer peptide antigen with N-tetradecanoyl L- serine-β-alanine-containing D-glucosamine derivative structurally related to lipid A as an immunoadjuvant were synthesized for the development of totally synthetic vaccines against cancers. The mitogenic activities of compounds 6 and 7 were stronger than that of lipid A analog 3.