22663-09-8Relevant articles and documents
"click" tetradentate ligands
Hao, Erhong,Wang, Zhaoyun,Jiao, Lijuan,Wang, Shaowu
, p. 2660 - 2666 (2010)
A series of triazole-based N4 tetradenate ligands 1a-d are efficiently synthesized using CuI-catalyzed azide-alkyne "click" strategy and are readily coordinated to many metal ions (e.g. MnII, NiII, ZnII and FeII). The X-ray structures of the resultant metal-complexes (4a-d, 5a, 6a and 7a) reveal an octahedral mononuclear structure with two co-ligands bonded in cis sites and the two triazoles as nitrogen donors to the metal center. The MnII-complexes (4a-d) show efficient catalytic activities in the epoxidation of various aliphatic terminal olefins with peracetic acid, and feature with low catalyst loading, fast conversion and high yields. The Royal Society of Chemistry 2010.
Total Synthesis of Four Isomers of the Proposed Structures of Cryptorigidifoliol K
Reddy, G. Sudhakar,Padhi, Birakishore,Bharath, Yada,Mohapatra, Debendra K.
, p. 6506 - 6509 (2017/12/26)
The first asymmetric convergent total synthesis of four isomers of proposed structures of cryptorigidifoliol K (1a, 1b, 1c, and 1d) has been achieved from commercially available starting materials. The key steps in this synthesis involve tandem isomerization followed by a C-O and C-C bond-forming reaction for the construction of trans-2,6-disubstituted dihydropyran, iodolactonization, isomerization of terminal alkene, and cross-metathesis reaction. The large discrepancies in the spectroscopic data (1H NMR) of synthetic cryptorigidifoliol K from the natural product suggest that the structure of the natural cryptorigidifoliol K requires revision.
An enzymatic approach to bifunctional chelating agents
Minazzi, Paolo,Lattuada, Luciano,Menegotto, Ivan G.,Giovenzana, Giovanni B.
, p. 6915 - 6921 (2014/10/15)
Bifunctional chelating agents (BFCAs) combine the complexing properties of a multidentate ligand with the presence of a free reactive functional group, mainly devoted to conjugation purposes. Indeed, products obtained by conjugation of a BFCA to a biomolecule and coordination of a suitable metal ion are widely applied in medicine nowadays as diagnostic and therapeutic agents. BFCAs are generally prepared through multi-step syntheses and with extensive application of protection-deprotection strategies, due to the large number of functional groups involved. Hydrolytic enzymes, with their unique chemoselectivity, provided the best results in the preparation of three different BFCAs based on very useful and well known ligand platforms. This journal is the Partner Organisations 2014.