226879-30-7

Upstream product

• 135006-32-5 4-tert-butyldiphenylsilyloxy-1-butene 
• 127047-71-6 3-(tert-butyldiphenylsilyloxy)propan-1-ol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 13291-18-4 isopropenylmagnesium bromide 
• 112897-03-7 3-(tert-butyldiphenylsilyloxy)-1-propanal 

Downstream Products

• 1093394-80-9 C₂₂H₂₈O₂Si 
• 226879-43-2 2-(benzoyloxy-{2-[6-(tert-butyl-diphenyl-silanyloxy)-3-methyl-hex-3-enyl]-[1,3]dithian-2-yl}-methyl)-5-methoxymethoxymethyl-furan-3-carboxylic acid methyl ester 
• 226879-36-3 [6-(2-{benzyloxy-[5-(tetrahydro-pyran-2-yloxymethyl)-furan-2-yl]-methyl}-[1,3]dithian-2-yl)-4-methyl-hex-3-enyloxy]-tert-butyl-diphenyl-silane 
• 226879-42-1 2-({2-[6-(tert-butyl-diphenyl-silanyloxy)-3-methyl-hex-3-enyl]-[1,3]dithian-2-yl}-hydroxy-methyl)-5-methoxymethoxymethyl-furan-3-carboxylic acid methyl ester 
• 226879-35-2 {2-[6-(tert-butyl-diphenyl-silanyloxy)-3-methyl-hex-3-enyl]-[1,3]dithian-2-yl}-[5-(tetrahydro-pyran-2-yloxymethyl)-furan-2-yl]-methanol 
• 226879-46-5 2-((E)-6-{2-[Benzoyloxy-(3-methoxycarbonyl-5-methoxymethoxymethyl-furan-2-yl)-methyl]-[1,3]dithian-2-yl}-4-methyl-hex-3-enyl)-malonic acid dimethyl ester 
• 226879-47-6 2-((E)-6-{2-[Benzoyloxy-(5-hydroxymethyl-3-methoxycarbonyl-furan-2-yl)-methyl]-[1,3]dithian-2-yl}-4-methyl-hex-3-enyl)-malonic acid dimethyl ester 
• 226879-39-6 2-[(E)-6-(2-{Benzyloxy-[5-(tetrahydro-pyran-2-yloxymethyl)-furan-2-yl]-methyl}-[1,3]dithian-2-yl)-4-methyl-hex-3-enyl]-malonic acid dimethyl ester 
• 226879-48-7 2-((E)-6-{2-[Benzoyloxy-(5-chloromethyl-3-methoxycarbonyl-furan-2-yl)-methyl]-[1,3]dithian-2-yl}-4-methyl-hex-3-enyl)-malonic acid dimethyl ester 
• 226879-45-4 2-{Benzoyloxy-[2-((E)-6-methanesulfonyloxy-3-methyl-hex-3-enyl)-[1,3]dithian-2-yl]-methyl}-5-methoxymethoxymethyl-furan-3-carboxylic acid methyl ester 
• 226879-38-5 Methanesulfonic acid (E)-6-(2-{benzyloxy-[5-(tetrahydro-pyran-2-yloxymethyl)-furan-2-yl]-methyl}-[1,3]dithian-2-yl)-4-methyl-hex-3-enyl ester 
• 226879-44-3 2-{Benzoyloxy-[2-((E)-6-hydroxy-3-methyl-hex-3-enyl)-[1,3]dithian-2-yl]-methyl}-5-methoxymethoxymethyl-furan-3-carboxylic acid methyl ester 
• 226879-37-4 (E)-6-(2-{Benzyloxy-[5-(tetrahydro-pyran-2-yloxymethyl)-furan-2-yl]-methyl}-[1,3]dithian-2-yl)-4-methyl-hex-3-en-1-ol 
• 226879-40-9 2-((E)-6-{2-[Benzyloxy-(5-hydroxymethyl-furan-2-yl)-methyl]-[1,3]dithian-2-yl}-4-methyl-hex-3-enyl)-malonic acid dimethyl ester 

Relevant academic research and scientific papers

Diastereoselective Synthesis of Highly Substituted Tetrahydrofurans by Pd-Catalyzed Tandem Oxidative Cyclization-Redox Relay Reactions Controlled by Intramolecular Hydrogen Bonding

Palladium-catalyzed oxidative cyclization of alkenols provides a convenient entry into cyclic ethers but typically proceeds with little or no diastereoselectivity for cyclization of trisubstituted olefins to form tetrahydrofurans due to the similar energi

New metal-free one-pot synthesis of substituted allenes from enones

(Chemical Equation Presented) A new metal-free, one-pot synthesis of substituted allenes from enones was discovered for the first time, in which a tertiary amine as a base was found to be an effective promoter in such novel transformations. The present synthetic protocol proceeded readily with high compatibility of sensitive functional groups, and it provides a new efficient way to access a series of synthetically important allenes without the use of metallic reagents or catalysts.

Transannular Diels-Alder model studies on the total synthesis of chatancin. The furanophane approach. Part 1: Assembly of the acyclic substrates

Synthesis of three generations of model substrates with advancing similarity to chatancin are presented. In the first two generations, an Ireland-Claisen based six-step sequence supplied the trans-dienophile to be connected by dithiane chemistry to furfurals. In the third generation, a homogeraniol based dienophile aldehyde was coupled with a dilithiated 3- furoic acid. Subsequently, all three generations were concluded with similar functional group modifications as a preparation for a malonate-furyl chloride based macrocyclization.