226930-88-7

Basic information

• Product Name: [1-(2-methylpropyl)-1H-imidazol-5-yl]methanol
• CAS NO: 226930-88-7
• Molecular Formula: C₈H₁₄N₂O
• Molecular Weight: 154.2096
• Mol File: 226930-88-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 326.913°C at 760 mmHg
• Flash Point: 151.512°C
• Density: 1.073g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.529
• CAS DataBase Reference: [1-(2-methylpropyl)-1H-imidazol-5-yl]methanol(CAS DataBase Reference)
• NIST Chemistry Reference: [1-(2-methylpropyl)-1H-imidazol-5-yl]methanol(226930-88-7)
• EPA Substance Registry System: [1-(2-methylpropyl)-1H-imidazol-5-yl]methanol(226930-88-7)

Safety Data

• Hazardous Substances Data: 226930-88-7(Hazardous Substances Data)

Usage

General Description

[1-(2-methylpropyl)-1H-imidazol-5-yl]methanol is a chemical compound with the molecular formula C9H14N2O. It is a derivative of imidazole and contains a 1H-imidazole ring with a methylpropyl group attached to the nitrogen atom at position 2. The compound also has a hydroxymethyl group attached to the carbon atom at position 5 of the imidazole ring. This chemical is commonly used in pharmaceutical research and synthesis, and it may have potential applications in the development of new medications or treatments. Its specific properties and potential uses may vary depending on the intended application and the context in which it is used.

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Relevant articles and documents

Structure-based design of imidazole-containing peptidomimetic inhibitors of protein farnesyltransferase

A series of imidazole-containing peptidomimetic PFTase inhibitors and their co-crystal structures bound to PFTase and FPP are reported. The structures reveal that the peptidomimetics adopt a similar conformation to that of the extended CVIM tetrapeptide,

Imidazole derivatives having an inhibitory activity for farnesyl transferase and process for preparation thereof

The present invention relates to a novel imidazole derivative represented by formula (1) which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts or isomers thereof, in which A, n1and Y are defined in the specification; to a process for preparation of the compound of formula (1); to intermediates which are used in the preparation of the compound of formula (1); and to a pharmaceutical composition comprising the compound of formula (1) as an active ingredient.