226940-56-3

Upstream product

• 76-83-5 trityl chloride 
• 226940-55-2 (2E,6E)-(S)-5-(tert-butyl-dimethyl-silanyloxy)-2-[(S)-5-(tert-butyl-dimethyl-silanyloxy)-4-methyl-pentyl]-6-methyl-7-(2-methyl-thiazol-4-yl)-hepta-2,6-dien-1-ol 
• 105859-46-9 (2R)-(tert-butyldimethyl)-(3-iodo-2-methylpropoxy)silane 
• 226940-54-1 (2E,6E)-(S)-5-(tert-butyl-dimethyl-silanyloxy)-2-[(S)-5-(tert-butyl-dimethyl-silanyloxy)-4-methyl-pentyl]-6-methyl-7-(2-methyl-thiazol-4-yl)-hepta-2,6-dienoic acid methyl ester 
• 226940-40-5 (S)-7-(tert-butyl-dimethyl-silanyloxy)-6-methyl-2-(triphenylphosphanylidene)-heptanoic acid methyl ester 
• 190369-75-6 (S)-6-(tert-Butyl-dimethyl-silanyloxy)-5-methyl-hexanal 
• 187756-76-9 [(2R)-3-bromo-2-methylpropoxy](1,1-dimethylethyl)dimethylsilane 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 226940-38-1 tert-butyl-dimethyl-(2-methyl-hept-6-enyloxy)-silane 
• 188730-01-0 6-tert-butyldimethylsilyloxy-5-methylhexan-1-ol 
• 188730-03-2 6-tert-butyldimethylsilyloxy-1-iodo-5-methylhexane 

Downstream Products

• 201136-71-2 (12E,16E)-(3S,6R,7S,8S,15S)-1,3,15-Tris-(tert-butyl-dimethyl-silanyloxy)-7-hydroxy-4,4,6,8,16-pentamethyl-17-(2-methyl-thiazol-4-yl)-12-trityloxymethyl-heptadeca-12,16-dien-5-one 
• 201136-73-4 (12E,16E)-(3S,6R,7S,8S,15S)-1,3,7,15-Tetrakis-(tert-butyl-dimethyl-silanyloxy)-4,4,6,8,16-pentamethyl-17-(2-methyl-thiazol-4-yl)-12-trityloxymethyl-heptadeca-12,16-dien-5-one 
• 201136-70-1 (6E,10E)-(2S,9S)-9-(tert-Butyl-dimethyl-silanyloxy)-2,10-dimethyl-11-(2-methyl-thiazol-4-yl)-6-trityloxymethyl-undeca-6,10-dienal 
• 226940-59-6 (6E,10E)-(2S,9S)-9-(tert-Butyl-dimethyl-silanyloxy)-2,10-dimethyl-11-(2-methyl-thiazol-4-yl)-6-trityloxymethyl-undeca-6,10-dien-1-ol 

Relevant academic research and scientific papers

Synthesis of 16-desmethylepothilone B: Improved methodology for the rapid, highly selective and convergent construction of epothilone B and analogues

During a synthesis of 16-desmethylepothilone B new methods for the convergent and highly stereoselective synthesis of epothilone B and analogues were developed.