226959-26-8

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 204327-17-3 (1S,3R,4R)-2-aza-bicyclo<2.2.1>heptane-3-carboxylic acid ethyl ester 

Downstream Products

• 226958-99-2 (1S,3R,4R)-3-Bromomethyl-2-(toluene-4-sulfonyl)-2-aza-bicyclo[2.2.1]heptane 
• 273721-40-7 [(1S,3R,4R)-2-(Toluene-4-sulfonyl)-2-aza-bicyclo[2.2.1]hept-3-yl]-methanol 

Relevant academic research and scientific papers

A novel synthesis of chiral cyclopentyl- and cyclohexyl-amines

A new route to multifunctionalised chiral cyclopentyl- and cyclohexyl-amines was developed by means of a new reaction involving the ring opening of a 2-azabicyclo-[2.2.1] or -[2.2.2] structure in high yields.

AZABICYCLO COMPOUND, MATRIX METALLOPROTEASE INHIBITOR, AND SKIN PREPARATION

An azabicyclo compound (I) or a salt thereof in accordance with the present invention has an excellent inhibiting action on matrix metalloproteases (MMPs) activity, and is useful for pharmaceutical, cosmetic and skin external compositions. wherein R is H,