226997-01-9Relevant academic research and scientific papers
Novel limonene phosphonate and farnesyl diphosphate analogues: Design, synthesis, and evaluation as potential protein-farnesyl transferase inhibitors
Eummer, Jeffrey T.,Gibbs, Barbara S.,Zahn, Todd J.,Sebolt-Leopold, Judith S.,Gibbs, Richard A.
, p. 241 - 250 (2007/10/03)
Limonene and its metabolite perillyl alcohol are naturally-occurring isoprenoids that block the growth of cancer cells both in vitro and in vivo. This cytostatic effect appears to be due, at least in part, to the fact that these compounds are weak yet sel
