227005-71-2Relevant academic research and scientific papers
Enantioselective synthesis of functionalized α-amino acids via a chiral guanidine catalyzed Michael addition reaction
Ma, Dawei,Cheng, Kejun
, p. 713 - 719 (2007/10/03)
Several chiral guanidines were evaluated as catalysts for the Michael reaction of glycine derivatives 7 with acrylic esters 8. The best result (30.4% ee) was obtained when 7b was reacted with 8b under the catalysis of guanidine 1 in THF.
