227008-07-3

Upstream product

• 126661-11-8 2-methyl-1-(4-nitrophenyl)-1-nitropropane 
• 6674-22-2 1,8-diazabicyclo[5.4.0]undec-7-ene 
• 594-09-2 trimethylphosphane 
• 1429345-88-9 [Ru^II(2,2′:6′,2″-terpyridine)(1-(2,2':6',2''-terpyridin-4'-yl)-3-(4-nitrophenyl)urea)]²⁺ 
• 1429345-86-7 (4'-phenylurea-2,2':6',2''-terpyridine)(2,2':6',2''-terpyridine)ruthenium(II) 

Downstream Products

• 1429345-86-7 (4'-phenylurea-2,2':6',2''-terpyridine)(2,2':6',2''-terpyridine)ruthenium(II) 
• 6674-22-2 1,8-diazabicyclo[5.4.0]undec-7-ene 
• 1429345-88-9 [Ru^II(2,2′:6′,2″-terpyridine)(1-(2,2':6',2''-terpyridin-4'-yl)-3-(4-nitrophenyl)urea)]²⁺ 

Relevant academic research and scientific papers

1,8-Diazabicycloundec-7-ene as a ligand in an intermediate in selective carbonyl substitution of a ruthenium-cobalt complex

1,8-Diazabicycloundec-7-ene, DBU, reacts with (OC)4Ru(μ-PPh2)Co(CO)3 (1) at room temperature to give an intermediate 2, which on protonation in the presence of CO regenerates 1 and on protonation in the presence of PMe3 gives the monosubstituted product (OC)3(L)Ru(μ-PPh2)Co(CO)3 (3 L=PMe3).DBU promotes the selective formation of 4 (L=PPh2Me) or 5 (L=Ph2PCH2C(Me)=CH2) in one-step from 1, Ph2PH, and methyl iodide or methallyl chloride, respectively.

Enhancing the anion affinity of urea-based receptors with a Ru(terpy) 22+ chromophore

Covalent linking of a Ru(terpy)22+ substituent improves recognition and sensing properties of the urea subunit toward anions. Urea's anion affinity is enhanced by the electrostatic attraction exerted by the RuII cation and by the electron-withdrawing effect exerted by the entire polypyridine-metal complex. Such an enhancement of the anion affinity, which results from the combination of a through-space and a through-bond effect, is greater than that exerted by the classical neutral electron-withdrawing substituent nitrophenyl. Small yet significant modifications of π-π* and MLCT bands of the Ru(terpy)22+ chromophore, detected through UV-vis spectrophotometric titrations, allowed the determination of the constants for the formation of receptor-anion H-bond complexes in diluted MeCN solution. On 1H NMR titration experiments, carried out under more concentrated conditions, the interaction of a second Cl- ion was observed, taking place through an outer-sphere mechanism. The Ru(terpy) 22+ substituent favors the deprotonation of a urea N-H fragment on addition of a second equivalent of fluoride, with formation of HF2-.

INFLUENCE OF WATER ON THE KINETICS OF THE REACTION OF NITROALKANES WITH AMINE BASES IN APROTIC SOLVENTS

The traces of water in reaction systems of nitroalkanes and amine bases in aprotic solvents caused a marked decrease of the reaction rate instead of its acceleration expected from possible triggering of side reactions effected by hydroxide ions or hydroxide ion pairs BH+, OH-.The kinetics and possible consequences in the mechanism of proton transfer are discussed.