22701-42-4

Basic information

• Product Name: (2-PYRIDIN-2-YL-ETHYLSULFANYL)-ACETIC ACID
• Synonyms: (2-PYRIDIN-2-YL-ETHYLSULFANYL)-ACETIC ACID
• CAS NO: 22701-42-4
• Molecular Formula: C9H11NO2S
• Molecular Weight: 197.25
• Mol File: 22701-42-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2-PYRIDIN-2-YL-ETHYLSULFANYL)-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (2-PYRIDIN-2-YL-ETHYLSULFANYL)-ACETIC ACID(22701-42-4)
• EPA Substance Registry System: (2-PYRIDIN-2-YL-ETHYLSULFANYL)-ACETIC ACID(22701-42-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 22701-42-4(Hazardous Substances Data)

Usage

General Description

(2-PYRIDIN-2-YL-ETHYLSULFANYL)-ACETIC ACID is a chemical compound with the molecular formula C9H9NO2S. It is a derivative of pyridine with a sulfur-containing side chain and a acetic acid (ethylsulfanyl) functional group. (2-PYRIDIN-2-YL-ETHYLSULFANYL)-ACETIC ACID is commonly used as a building block in organic synthesis and pharmaceutical research. It has potential applications in the development of new drugs and medicinal compounds due to its unique structure and properties. Additionally, it may have uses as a reagent in chemical reactions or as a precursor to other more complex molecules.

Upstream product

• 2044-28-2 (pyridyl-2)-2 ethanethiol 
• 79-11-8 chloroacetic acid 
• 100-69-6 2-vinylpyridine 
• 68-11-1 mercaptoacetic acid 

Relevant articles and documents

Rhenium(I) and Technetium(I) tricarbonyl complexes with [NSO]-type chelators: Synthesis, structural characterization, and radiochemistry

The reactions of the NSO ligands 2-[2-(pyridin-2-yl)ethylthio]acetic acid (HL1), 3-[2-(pyridin-2-yl)ethylthio]propanoic acid (HL2), 2-(carboxymethylthio)- 3-(1H-imidazol-4-yl)propanoic acid (H2L3), and 2-(carboxyethylthio)- 3-(1H-imidazol-4-yl)propanoic acid (H2L4) with [NEt4] 2[ReBr3(CO)3] are presented. Ligands HL1, H2L3, and H2L4 act as tridentate NSO chelators and readily generate the fac-[Re(NSO)(CO)3]complexes Re-L1, Re-HL3, and Re-HL4. Ligand HL2 acts as NSO tridentate chelator only in the presence of base to give complex Re-L2, while without base it coordinates as a NS bidentate chelator to generate complex fac-[ReBr(NS)(CO)3], Re-HL2. All complexes were isolated and characterized by elemental analysis, IR and 1H, 13C NMR spectroscopy. Complex Re-L1, Re-HL2, and Re-HL3 were characterized also by X-ray crystallography. Furthermore, the analogous technetium complexes fac-[99mTc(NSO)(CO)3]+, 99mTc-L1, 99mTc-L2, 99mTc-HL3, and 99mTc-HL4 were synthesized by reacting ligands HL1-H2L4 with the fac-[99mTc(OH2)3(CO)3] + precursor for 30 min at 75 °C. The tracer complexes 99mTc-L1-99mTc-HL4 were found to be stable in L-cysteine and L-histidine challenge experiments. The bifunctional chelating agents that bear a second carboxylate group are promising for the development of targeted 99mTc radiopharmaceuticals.