227180-22-5Relevant academic research and scientific papers
Synthesis of new melatoninergic ligands including azaindole moiety
Mazéas, Daniel,Guillaumet, Gérald,Viaud, Marie-Claude
, p. 1065 - 1080 (2007/10/03)
A novel series of melatonin analogues, based on the azaindole nucleus is described. These compounds are prepared in several steps directly from the commercial available 7-azaindole or from substituted amino-, iodo- or/and nitropyridines using a catalysed palladium reaction or vicarious nucleophilic substitution of hydrogen (VNS) in order to elaborate the 6-, 5- and 4- azaindole derivatives respectively.
