22725-58-2Relevant academic research and scientific papers
A selective fluorogenic chemodosimeter for Hg2+ based on the dimerization of desulfurized product
Zhang, Peng,Shi, Bingbing,Zhang, Youming,Lin, Qi,Yao, Hong,You, Xingmei,Wei, Taibao
, p. 10292 - 10298 (2013)
A simple Hg2+-selective chemodosimetric system based on thiosemicarbazone was investigated. The transformation of thiosemicarbazone into semicarbazone selectively exerted by Hg2+ ions and the dimerization of semicarbazone resulted in a pronounced OFF-ON-type fluorescent signaling behavior. The coexistent metal ions, such as Fe3+, Ca2+, Cu2+, Co2+, Ni2+, Cd2+, Pb 2+, Zn2+, Cr3+, Mg2+, Na +, K+, and Fe2+, had no obvious interference with the detection of Hg2+. In addition, S12-Hg 2+ plays a high sensitivity for basic anions to form an 'OFF-ON-OFF' type signaling behavior, with the Hg2+-induced emission spectra can be quenched. Moreover, test strips based on S12 exhibited a good selectivity to Hg2+. We believe the test strips could act as a convenient and efficient Hg2+ test kit.
Synthesis and in vitro evaluation of new nitro-substituted thiazolyl hydrazone derivatives as anticandidal and anticancer agents
Altintop, Mehlika Dilek,?zdemir, Ahmet,Turan-Zitouni, Gülhan,Ilgin, Sinem,Atli, ?zlem,Demirci, Fatih,Kaplancikli, Zafer Asim
, p. 14809 - 14820 (2015/02/19)
Fourteen new thiazolyl hydrazone derivatives were synthesized and evaluated for their anticandidal activity using a broth microdilution assay. Among the synthesized compounds, 2-[2-((5-(4-chloro-2-nitrophenyl)furan-2-yl)methylene)hydrazinyl]- 4-(4-fluorop
Synthesis of some new 2,4-disubstituted thiazoles as possible antibacterial and anti-inflammatory agents
Holla, B. Shivarama,Malini,Rao, B. Sooryanarayana,Sarojini,Kumari, N. Suchetha
, p. 313 - 318 (2007/10/03)
A series of arylthioureas (1), aromatic aldehyde thiosemicarbazones (2) and 5-aryl-2-furfuraldehyde thiosemicarbazones (3) were condensed with 2,4-dichloro-5-fluorophenacyl bromide to yield respective arylaminothiazoles, arylidene/5-aryl-2-furfurylidene hydrazinothiazoles (4). The newly synthesized compounds were characterized by IR, 1H-NMR and mass spectral studies. These compounds were also screened for their antibacterial and anti-inflammatory activities. Two of the newly synthesized compounds showed anti-inflammatory activity comparable with that of Ibuprofen.
