227316-48-5

Basic information

• Product Name: 5-Isoxazolecarboxylicacid,3-amino-4-(ethylamino)-,ethylester(9CI)
• Synonyms: 5-Isoxazolecarboxylicacid,3-amino-4-(ethylamino)-,ethylester(9CI)
• CAS NO: 227316-48-5
• Molecular Formula: C8H13N3O3
• Molecular Weight: 0
• Product Categories: AMINOACID
• Mol File: 227316-48-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Isoxazolecarboxylicacid,3-amino-4-(ethylamino)-,ethylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Isoxazolecarboxylicacid,3-amino-4-(ethylamino)-,ethylester(9CI)(227316-48-5)
• EPA Substance Registry System: 5-Isoxazolecarboxylicacid,3-amino-4-(ethylamino)-,ethylester(9CI)(227316-48-5)

Safety Data

• Hazardous Substances Data: 227316-48-5(Hazardous Substances Data)

Upstream product

• 227316-25-8 Diethyl 2-(1-ethyl-2-methyl-4-nitro-1H-imidazol-5-yl)propane-1,3-dioate 
• 227316-35-0 Ethyl 4-ethyl-5-methyl-4H-imidazo<4,5-c>isoxazole-3-carboxylate 

Relevant articles and documents

Synthesis of the first examples of the imidazo[4,5-c]isoxazole ring system

The synthesis of the first examples of the 4H-imidazo[4,5-c]isoxazole ring system are reported. These compounds are obtained in good yield by thermolysis of 2-(4-nitro-1H-imidazol-5-yl) acetate and malonate derivatives, in turn readily available from reaction of 5-chloro-4-nitro-1H-imidazoles with active methylene compounds. The X-ray crystal structure of an imidazo[4,5-c][1,2]oxazine derived from a proposed intermediate has been obtained and a mechanism for the reaction is discussed.