227323-50-4Relevant academic research and scientific papers
Base-controlled chemoselectivity: direct coupling of alcohols and acetonitriles to synthesise α-alkylated arylacetonitriles or acetamides
Bai, Liang,Ge, Min-Tong,Li, Chen,Qiu, Yuan-Rui,Wang, Ying,Xia, Ai-Bao,Xu, Dan-Qian
supporting information, p. 15200 - 15204 (2021/09/06)
We achieved chemoselective synthesis of α-alkylated arylacetonitriles and acetamides by combining Ir complex-catalysed direct coupling of alcohols and nitriles by a simple adjustment of the base. Methanol and ethanol performed well as the alkylating reagents. This method of acetonitrile alkylation provided a novel approach for carbon chain extension.
Catalyst-Controlled C-H Functionalization of Adamantanes Using Selective H-Atom Transfer
Yang, Hai-Bin,Feceu, Abigail,Martin, David B. C.
, p. 5708 - 5715 (2019/06/07)
A method for the direct functionalization of diamondoids has been developed using photoredox and H atom transfer catalysis. This C-H alkylation reaction has excellent chemoselectivity for the strong 3° C-H bonds of adamantanes in polyfunctional molecules.
1-(adamantyl)amidines and their use in the treatment of conditions generally associated with abnormalities in glutamatergic transmission
-
, (2008/06/13)
Compounds of 1-(adamantyl) amidine and their use in the treatment of conditions generally associated with abnormalities in glutamatergic transmittion.
