227327-31-3

Upstream product

• 56234-52-7 1,8-bis(p-toluenesulfonyloxy)-3,6-bis(p-toluenesulfonyl)-3,6-diazaoctane 
• 539-48-0 p-xylylidenediamine 
• 623-24-5 1,4-bis(bromomethyl)benzene 
• 95388-08-2 N,N'-bis(p-toluenesulfonyl)-1,4,7-triazacyclononane 

Relevant academic research and scientific papers

A remarkably efficient and direct route for the synthesis of binucleating 1,4,7-triazacyclononane ligands

An extremely efficient and direct route towards a range of binucleating analogues of 1,4,7-triazacyclononane 5a-f, has been developed. In all cases the reactions of benzylic and aliphatic diamines with ditosylate ester 3 proceed to give the target binucleating ligands ahnost exclusively and in excellent yield.

Dinuclear copper(II) complexes that promote hydrolysis of GpppG, a model for the 5′-cap of mRNA

The hydrolysis of the monoribonucleotide GpppG, a model compound for the 5′-cap structure of mRNA, by dinuclear Cu(II) complexes of triazacyclononane was 100-fold more rapid than in the presense of the analogous mononuclear complex; a first-order or second-order dependence on the catalyst was observed for two different dinuclear complexes.