22748-65-8Relevant academic research and scientific papers
SYNTHESIS AND REACTIVITY OF A STABLE PRECURSOR OF 2-CYANO-1,3-BUTADIENE
Baraldi, Pier Giovanni,Barco, Achille,Benetti, Simonetta,Manfredini, Stefano,Pollini, Gian Piero,et.al.
, p. 6451 - 6454 (2007/10/02)
A new, productive synthesis of 3-cyano-2,5-dihydrothiophene-1,1-dioxide (3) is described.This substituted sulfolene serves as a stable precursor of 2-cyano-1,3-butadiene and can be used in the Diels-Alder reactions without isolation of the unstable diene.The Diels-Alder reactions of 2-cyano-1,3-butadiene appear to proceed in high yield only with electron-deficient dienophiles, but (13)C NMR shows that in some cases the products are a mixture of regioisomeric cycloadducts.
