227616-76-4

Upstream product

• 227616-75-3 (S)-6-(tert-butoxycarbonyl)-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-3-carboxylic Acid 
• 100-51-6 benzyl alcohol 

Downstream Products

• 639831-23-5 3-benzyloxycarbonylamino-6-methyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic Acid tert-butyl Ester 
• 227616-77-5 (6S)-3-{[(Benzyloxy)carbonyl]amino}-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-6-carboxylic acid 

Relevant academic research and scientific papers

Bicyclic pyrimidinones as coagulation cascade inhibitors

The present invention relates generally to compounds that inhibit serine proteases. In particular it is directed to novel amino-bicyclic pyrimidinone compounds of Formula (I): or a stereoisomer or pharmaceutically acceptable salt form thereof, which are u

Inhibitors of hepatitis C virus NS3 protease

The present invention relates generally to a novel class of pyrimidinones of Formula (I): that are useful as serine protease inhibitors, and more particularly as Hepatitis C virus NS3 protease inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of using the same.