227619-06-9

Upstream product

• 227618-83-9 (2S-(2α(S*),3aα,4β,7β,7aα))-(phenylmethyl) N-(2-(3-chloro-4,5-di(phenylmethoxy)-phenyl)-2-((octahydro-7,8,8-trimethyl-4,7-methano-benzofuran-2-yl)oxy)-ethyl)-carbamate 
• 227618-87-3 (2S-(2α(S*),3aα,4β,7β,7aα))-(phenylmethyl) N-(2-(3-chloro-4,5-di(phenylmethoxy)-phenyl)-2-((octahydro-7,8,8-trimethyl-4,7-methano-benzofuran-2-yl)oxy)-ethyl)-N-methylcarbamate 
• 227618-77-1 (2S-(2α(S*),3aα,4β,7β,7aα))-3-chloro-α-((octahydro-7,8,8-trimethyl-4,7-methano-benzofuran-2-yl)oxy)-4,5-di(phenylmethoxy)-benzeneethanamine 
• 227618-91-9 (R)-(phenylmethyl) N-(2-(3-chloro-4,5-di(phenylmethoxy)-phenyl)-2-hydroxyethyl)-N-methylcarbamate 
• 108-24-7 acetic anhydride 

Relevant academic research and scientific papers

Aminoalcohols V [1]: A method for the synthesis of enantiomerically pure ring-chlorinated epinephrines and norepinephrines

The synthesis of enantiomerically pure 5-and 6-chloroepinephrine hydrochloride, resp., as well as 6-chloronorepinephrine hydrochloride is described starting from ring chlorinated O-benzylated dihydroxybenzaldehyde cyanohydrins, which are O-protected using