Cas 227623-30-5,N-(5-tert-butyl-thien-3-yl)-N'-(2,3-dichlorophenyl)urea

227623-30-5

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Basic information

Product Name: N-(5-tert-butyl-thien-3-yl)-N'-(2,3-dichlorophenyl)urea
Synonyms: N-(5-tert-butyl-thien-3-yl)-N'-(2,3-dichlorophenyl)urea
CAS NO:227623-30-5
Molecular Formula:
Molecular Weight: 343.277
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: N-(5-tert-butyl-thien-3-yl)-N'-(2,3-dichlorophenyl)urea(CAS DataBase Reference)
NIST Chemistry Reference: N-(5-tert-butyl-thien-3-yl)-N'-(2,3-dichlorophenyl)urea(227623-30-5)
EPA Substance Registry System: N-(5-tert-butyl-thien-3-yl)-N'-(2,3-dichlorophenyl)urea(227623-30-5)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 227623-30-5(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 227623-30-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,7,6,2 and 3 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 227623-30:
(8*2)+(7*2)+(6*7)+(5*6)+(4*2)+(3*3)+(2*3)+(1*0)=125
125 % 10 = 5
So 227623-30-5 is a valid CAS Registry Number.

227623-30-5Upstream product

227623-30-5Downstream Products

227623-30-5Relevant academic research and scientific papers

Discovery of a new class of p38 kinase inhibitors

Dumas, Jacques,Sibley, Robert,Riedl, Bernd,Monahan, Mary Katherine,Lee, Wendy,Lowinger, Timothy B.,Redman, Aniko M.,Johnson, Jeffrey S.,Kingery-Wood, Jill,Scott, William J.,Smith, Roger A.,Bobko, Mark,Schoenleber, Robert,Ranges, Gerald E.,Housley, Timothy J.,Bhargava, Ajay,Wilhelm, Scott M.,Shrikhande, Alka

, p. 2047 - 2050 (2000)

The MAP kinase p38 has been implicated in cytokine signaling, and its inhibitors are potentially useful for the treatment of arthritis and osteoporosis. Novel small-molecule inhibitors of p38 kinase were derived from a combinatorial chemistry effort and e

INHIBITION OF P38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS

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Page/Page column 24-25, (2012/03/10)

This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases, other than cancer and proteolytic enzyme mediated diseases, other than cancer, and pharmaceutical compositions for use in such therapy.

INHIBITION OF RAF KINASE USING ARYL AND HETEROARYL SUBSTITUTED HETEROCYCLIC UREAS

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Page/Page column 10, (2008/06/13)

Methods of treating tumors mediated by raf kinase, with substituted urea compounds, and such compounds per se,

INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS

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Page/Page column 25, (2010/11/28)

Methods of treating tumors mediated by raf kinase, with substituted urea compounds, and such compounds per se.

INHIBITION OF RAF KINASE USING ARYL AND HETEROARYL SUBSTITUTED HETEROCYCLIC UREAS

-

Page/Page column 16, (2010/11/08)

Methods of treating tumors mediated by raf kinase, with substituted urea compounds, and such compounds per se.

INHIBITION OF p38 KINASE ACTIVITY USING ARYL AND HETEROARYL SUBSTITUTED HETEROCYCLIC UREAS

-

Page/Page column 18, (2010/11/24)

This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases other than cancer and proteolytic enzyme mediated diseases other than cancer, and pharmaceutical compositions for use in such therapy.

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