22767-87-9Relevant academic research and scientific papers
Nucleophilic Reactivity of N-Phosphorylated Ethyleneimine
Roux, Charlotte Le,Modro, Agnes M.,Modro, Tomasz A.
, p. 100 - 101 (2007/10/03)
The diesters of N-phosphorylated ethyleneimine (aziridine) are unreactive towards alkylating agents, but after being converted into the ionic monoesters, they undergo facile N-methylation with MeI, followed by fast opening at the aziridinium ring by the iodide ion; the results can be related to the bis-alkylating reactivity of N-phosphorylated nitrogen mustards.
