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Cycloprotobuxine A is a naturally occurring chemical compound belonging to the family of cyclobuxane diterpenoid alkaloids. It is primarily found in the plant species Buxus sempervirens, commonly known as the common boxwood. This complex molecule exhibits a unique cyclobutane ring structure and is characterized by its potent biological activities, including cytotoxic, antitumor, and antimicrobial properties. Cycloprotobuxine A has been the subject of extensive research due to its potential therapeutic applications, particularly in the development of novel anticancer drugs. Its chemical structure and biological properties make it an intriguing target for further investigation in the field of natural product chemistry and drug discovery.

2278-38-8

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2278-38-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2278-38-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,7 and 8 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 2278-38:
(6*2)+(5*2)+(4*7)+(3*8)+(2*3)+(1*8)=88
88 % 10 = 8
So 2278-38-8 is a valid CAS Registry Number.
InChI:InChI=1/C28H50N2/c1-19(29(6)7)20-12-14-26(5)22-11-10-21-24(2,3)23(30(8)9)13-15-27(21)18-28(22,27)17-16-25(20,26)4/h19-23H,10-18H2,1-9H3/t19-,20+,21-,22-,23-,25+,26-,27+,28-/m0/s1

2278-38-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Cycloprotobuxine-A

1.2 Other means of identification

Product number -
Other names Cycloprotobuxin-A

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2278-38-8 SDS

2278-38-8Downstream Products

2278-38-8Relevant academic research and scientific papers

BUXUS ALKALOIDS. PART XI. THE SYNTHESIS OF CYCLOPROTOBUXINE-A (3β,20S-CHIRALITY) AND ITS TWO ISOMERIC ALKALOIDS WITH 3β,20R- AND 3α,20R- CONFIGURATION FROM LANOSTEROL.

Nakano, Tatsuhiko,Martin, Alfonso,Alonso, Miguel

, p. 2957 - 2968 (2007/10/02)

The synthesis of cycloprotobuxine-A (5), representative of Buxus alkaloids, and its two isomeric alkaloids with 3β,20R- and 3α,20R-configuration, from lanosterol, is described.In order to confirm the stereochemistries at C-3 and C-20 in these three alkaloids, the 3β-dimethylamino-(27) and the 3α-dimethylamino derivative (28) of cycloartanol (24) were also synthesised and their 1H and 13C n.m.r.spectra are discussed.

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