22780-56-9Relevant academic research and scientific papers
One-pot preparation of pyrrole derivatives via the copper-catalyzed [4+1] annulation of propargylic amines with ethyl glyoxylate and phenylglyoxal in the presence of piperidine
Sakai, Norio,Suzuki, Hiroki,Hori, Hiroaki,Ogiwara, Yohei
, p. 63 - 66 (2017)
We describe how copper(II) chloride efficiently catalyzes the [4+1] annulation of propargylamines with either ethyl glyoxylate or phenylglyoxal functioning as a C1 unit, in the presence of piperidine, which leads to a straightforward and one-pot preparati
