22784-34-5

Upstream product

• 17702-41-9 nido-decaborane 
• 2789-88-0 1,2-bis(4-methylphenyl)acetylene 
• 16872-09-6 1,2-dicarba-closo-dodecaborane⁽¹²⁾ 
• 624-31-7 4-tolyl iodide 

Relevant academic research and scientific papers

Low-temperature 1,2 →1,7 isomerization of sterically crowded icosahedral closo-((2,3,8-η3):(5,6-η2)- norbornadien-2-yl)rhodacarborane via the formation of a pseudocloso intermediate.

The metalation reaction of the K+ salt of the carborane anion [7,8-(4'-MeC6H4)2-7,8-nido-C2B 9H10]- (1) with [((2,3,5,η4)-C 7H7-2-CH2OH)RhCl]2 (2) in a solution of CHCl3 or C6H6 at ambient temperature produced two diastereomeric closo complexes, [2,2-((2,3,8-η3):(5, 6-η2)C7H7CH2)-1,8-(4'MeC 6H4)2-2,1,8-closo-RhC2B 9H9] (5 and 6), the products of the low-temperature 1,2 → 1,7 carbon atom isomerization of a (nonisolable) [3,3-((2,3,8-η3): (5,6-η2)-C7H 7CH2)-1,2-(4'-MeC6H4) 2-3,1,2-closo-RhC2B9H9]. The overall architecture and stereochemistry of diastereomers 5 and 6 have been determined crystallographically. It has been established that the isomerization reaction proceeds through the intermediate pseudocloso type complex [3,3-((2,3,8-η3):(5,6-η2) -C7H7CH2)-1,2-(4'-MeC6H 4)2 3,l,2-pseudoleloso-RhC2B 9H9] (4), which was isolated and characterized by microanalysis, multinuclear NMR spectroscopy, and a single-crystal X-ray diffraction study.

Metal-Free Oxidative B?N Coupling of nido-Carborane with N-Heterocycles

A general method for the oxidative substitution of nido-carborane (7,8-C2B9H12?) with N-heterocycles has been developed by using 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) as an oxidant. This metal-free B?N coupling strategy, in both inter- and intramolecular fashions, gave rise to a wide array of charge-compensated, boron-substituted nido-carboranes in high yields (up to 97 %) with excellent functional-group tolerance under mild reaction conditions. The reaction mechanism was investigated by density-functional theory (DFT) calculations. A successive single-electron transfer (SET), B?H hydrogen-atom transfer (HAT), and nucleophilic attack pathway is proposed. This method provides a new approach to nitrogen-containing carboranes with potential applications in medicine and materials.

Nickel-catalyzed cross-coupling reactions of o-carboranyl with aryl iodides: Facile synthesis of 1-aryl-o-carboranes and 1,2-diaryl-o-carboranes

A nickel-catalyzed arylation at the carbon center of o-carborane cages has been developed, thus leading to the preparation of a series of 1-aryl-o-carboranes and 1,2-diaryl-o-carboranes in high yields upon isolation. This method represents the first examp