227939-09-5Relevant academic research and scientific papers
Non-peptide αvβ3 antagonists. Part 3: Identification of potent RGD mimetics incorporating novel β-amino acids as aspartic acid replacements
Coleman, Paul J,Brashear, Karen M,Hunt, Cecilia A,Hoffman, William F,Hutchinson, John H,Breslin, Michael J,McVean, Carol A,Askew, Ben C,Hartman, George D,Rodan, Sevgi B,Rodan, Gideon A,Leu, Chih-Tai,Prueksaritanont, Thomayant,Fernandez-Metzler, Carmen,Ma, Bennett,Libby, Laura A,Merkle, Kara M,Stump, Gary L,Wallace, Audrey A,Lynch, Joseph J,Lynch, Robert,Duggan, Mark E
, p. 31 - 34 (2002)
Potent non-peptidic αvβ3 antagonists have been prepared incorporating various β-amino acids as aspartic acid mimetics. Modification of the β-alanine 3-substituents alters the potency and physicochemical properties of these receptor a
