228249-01-2Relevant academic research and scientific papers
A simple synthesis of 3-phosphonyl-4-aminoquinolines from β- enaminophosphonates
Palacios, Francisco,Ochoa De Retana, Ana M.,Oyarzabal, Julen
, p. 5947 - 5964 (2007/10/03)
An easy and efficient synthesis of 4-aminoquinolines substituted with a phosphorylated group or a phosphine oxide group in the 3-position is described. The key step is a regioselective addition of lithiated β-enamino phosphonates to isocyanates to give fu
