22834-71-5Relevant academic research and scientific papers
Design and synthesis of A3 adenosine receptor ligands, 3′-fluoro analogues of Cl-IB-MECA
Kim, Hea Ok,Lim, Moo Hong,Park, Jae Gyu,Moon, Hyung Ryong,Jacobson, Kenneth A.,Kim, Hee-Doo,Chun, Moon Woo,Jeong, Lak Shin
, p. 923 - 925 (2003)
Synthesis of 3′-deoxy-3′-fluoro-N6-substituted adenosines as bioisosteres of Cl-IB-MECA and their binding affinities to A 3 adenosine receptor are described.
NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT
-
, (2010/05/13)
The invention provides unsaturated phosphonates of Formula I or a tautomer or pharmaceutically accepatble salt thereof, as described herein, as well as pharmaceutical compositions comprising the compounds, and therapeutic methods comprising administering the compounds. The compounds have anti-viral properties and are useful for treating viral infections (e.g. HCV) in animals (e.g. humans).
