228410-39-7Relevant academic research and scientific papers
COMPOUNDS USEFUL AS PHOSPHOTYROSINE MIMICS
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Page 15; 16, (2010/02/07)
New uses are disclosed for compositions containing compounds of formula (I) wherein A, B, C, G, Q and R are defined herein. The compositions inhibit the binding of tyrosine kinase-dependent regulatory proteins to their native phosphotyrosine-containing li
Nonpeptidic, monocharged, cell permeable ligands for the p56lck SH2 domain
Proudfoot,Betageri,Cardozo,Gilmore,Glynn,Hickey,Jakes,Kabcenell,Kirrane,Tibolla,Lukas,Patel,Sharma,Yazdanian,Moss,Beaulieu,Cameron,Ferland,Gauthier,Gillard,Gorys,Poirier,Rancourt,Wernic,Montse
, p. 2421 - 2431 (2007/10/03)
p56lck is a member of the src family of tyrosine kinases and plays a critical role in the signal transduction events that lead to T cell activation. Ligands for the p56lck SH2 domain have the potential to disrupt the interaction of p56lck with its substra
