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228418-81-3

(±)-LY 426965 dihydrochloride is a research chemical that functions as a selective antagonist for the group II metabotropic glutamate receptors (mGluR2 and mGluR3). It is utilized in scientific studies to explore the role of these receptors in various physiological and pathological processes, such as pain perception, neuroprotection, and drug addiction.
Used in Pharmaceutical Research:
(±)-LY 426965 dihydrochloride is used as a research tool for investigating the role of mGluR2 and mGluR3 receptors in physiological and pathological processes. By blocking the activity of these receptors, it aids researchers in understanding their function and potentially identifying new targets for therapeutic interventions related to glutamate signaling imbalances.
Used in Central Nervous System Studies:
(±)-LY 426965 dihydrochloride is used as a pharmacological agent for studying the role of mGluR2 and mGluR3 in the central nervous system. Its properties make it valuable for developing a deeper understanding of these receptors' impact on neurological functions and for creating novel pharmacological agents that target these receptors.

228418-81-3

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228418-81-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 228418-81-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,8,4,1 and 8 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 228418-81:
(8*2)+(7*2)+(6*8)+(5*4)+(4*1)+(3*8)+(2*8)+(1*1)=143
143 % 10 = 3
So 228418-81-3 is a valid CAS Registry Number.

228418-81-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-Cyclohexyl-4-[4-(2-methoxyphenyl)-1-piperazinyl]-2-methyl-2-phe nyl-1-butanone dihydrochloride

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:228418-81-3 SDS

228418-81-3Upstream product

228418-81-3Downstream Products

228418-81-3Relevant articles and documents

Arylpiperazines having activity at the serotonin 1A receptor

-

, (2008/06/13)

A series of aryl piperazine compounds are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1A receptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.

Arylpiperazines having activity at the serotonin 1A receptor

-

, (2008/06/13)

A series of aryl piperazine compounds of the formula: or the pharmaceutically acceptable salts thereof, are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1Areceptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.

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