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Z-Gly-S-Ala-S-Leu-OBzl is a peptide compound consisting of six amino acids: Z (a protecting group), Glycine (Gly), Alanine (Ala), Leucine (Leu), and two Serine (Ser) residues. The "S" in the sequence indicates that the serine residues are in their sulfide form, which means they have undergone a chemical modification to form a disulfide bond between them. The "OBzl" at the end signifies the presence of a benzyl protecting group, which is used to prevent unwanted side reactions during peptide synthesis. This specific sequence and structure are important in the field of peptide chemistry, as they can be used to study protein folding, stability, and interactions, as well as for the development of new drugs and therapeutics.

22849-48-5

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22849-48-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 22849-48-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,8,4 and 9 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 22849-48:
(7*2)+(6*2)+(5*8)+(4*4)+(3*9)+(2*4)+(1*8)=125
125 % 10 = 5
So 22849-48-5 is a valid CAS Registry Number.

22849-48-5Downstream Products

22849-48-5Relevant academic research and scientific papers

Effect of Tertiary Bases on O-Benzotriazolyluronium Salt-Induced Peptide Segment Coupling

Carpino, Louis A.,El-Fahman, Ayman

, p. 695 - 698 (2007/10/02)

Collidine activation of O-(7-azabenzotriazolyl)uronium salts leads to relatively low levels of racemization in the coupling of peptide segments, especially with reagents derived from 1,1-carbonyldipyrrolidine

1-ISOPROPYLALLYLOXYCARBONYL (IPAoc) AS A PROTECTIVE GROUP OF AMINES AND ITS DEPROTECTION CATALYSED BY PALLADIUM-PHOSPHINE COMPLEX

Minami, Ichiro,Yuhara, Masami,Tsuji, Jiro

, p. 2737 - 2740 (2007/10/02)

As a new protective group of amines, 1-isopropylallyloxycarbonyl (IPAoc) group was developed.IPAoc group can be removed by treatment with a palladium-phosphine catalyst forming carbon dioxide and 4-methyl-1,3-pentadiene by the decarboxylation and β-hydrogen elimination of (?-1-isopropylallyl)-palladium intermediate under neutral condititons.The present protection-deprotection was applied to a one-pot peptide synthesis.

STUDIES ON AMINO ACIDS AND PEPTIDES-III. 2,4-BIS(4-METHOXYPHENYL)-1,3,2,4-DITHIADIPHOSPHETANE 2,4-DISULFIDE, LR, AS A NEW RACEMIZATION FREE COUPLING REAGENT IN PEPTIDE SYNTHESIS

Pedersen, U.,Thorsen, M.,El-Khrisy, E. -E. A. M.,Clausen, K.,Lawesson, S. -O.

, p. 3267 - 3269 (2007/10/02)

The easily accesable 2,4-bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane 2,4-disulfide, LR, has been reacted with salts of N-protected amino acids 1 (Z-Gly-OH, Boc-Gly-OH, Boc-S-Ser(Bzl)-OH, Bos-S-Tyr(Bzl)-OH, Z-S-Arg(Z2)-OH, and Z-S-Pro-OH), at room tem

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