228573-35-1

Upstream product

• 348135-70-6 (R)-2-(1-tert-butoxycarbonyl)ethyl-1-ethoxycarbonyl-2-methylenecyclohexane 
• 348135-64-8 (R)-1-(2-tert-Butoxycarbonyl-ethyl)-2-oxo-cyclohexanecarboxylic acid ethyl ester 
• 21047-57-4 diethyl (1-diazo-2-oxopropyl)phosphonate 
• 348135-71-7 (R)-1-ethoxycarbonyl-1-(2-formyl)ethyl-2-methylenecyclohexane 

Relevant academic research and scientific papers

Investigation of the synthesis of angular tricyclic compounds by intramolecular Pauson-Khand reaction of exo- and endo-cyclic enynes

Intramolecular Pauson-Khand reaction of various alkynyl exo-alkylidene-cyclohexanes and -pentane gives angular type 6-5-5 and 5-5-5 tricyclic compounds in good to high yield. The present reaction also offers convenient construction of two contiguous quaternary centers, which could not be synthesized from alkynyl endo-cycloolefins. Scope and limitation of the present reaction of various exo- and endo-cyclic enynes are also described.