2287-10-7

Basic information

• Product Name: 1-[2-(2-methoxy-4-nitrophenoxy)ethyl]pyrrolidine
• CAS NO: 2287-10-7
• Molecular Formula: C₁₃H₁₈N₂O₄
• Molecular Weight: 266.293
• Mol File: 2287-10-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 414.9°C at 760 mmHg
• Flash Point: 204.7°C
• Density: 1.201g/cm³
• Vapor Pressure: 4.29E-07mmHg at 25°C
• Refractive Index: 1.552
• CAS DataBase Reference: 1-[2-(2-methoxy-4-nitrophenoxy)ethyl]pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-(2-methoxy-4-nitrophenoxy)ethyl]pyrrolidine(2287-10-7)
• EPA Substance Registry System: 1-[2-(2-methoxy-4-nitrophenoxy)ethyl]pyrrolidine(2287-10-7)

Safety Data

• Hazardous Substances Data: 2287-10-7(Hazardous Substances Data)

Usage

Structure

Contains a pyrrolidine ring and a nitrophenyl ether linkage

Application

Used in scientific research as a potential inhibitor of the monoamine transporter protein

Function

Regulates levels of neurotransmitters such as dopamine and serotonin in the brain

Potential Effects

May affect mood, cognition, and behavior

Therapeutic Potential

May have applications in the treatment of psychiatric and neurological disorders

Research Status

Precise mechanism of action and therapeutic potential are still being investigated

Safety Precautions

Should be handled and used with caution due to potential hazardous properties

Laboratory Use

Requires proper safety measures in laboratory settings

Upstream product

• 5050-41-9 N-(2-chloroethyl)-pyrrolidine 
• 3251-56-7 2-methoxy-4-nitrophenol 
• 7250-67-1 1-(2-chloroethyl)pyrrolidine hydrochloride 
• 100200-99-5 potassium 2-methoxy-4-nitrophenolate monohydrate 
• 1009-36-5 2-chloro-5-nitroanisole 

Downstream Products

• 1400664-28-9 C₂₇H₂₉N₃O₄ 
• 1400664-06-3 C₂₆H₂₇N₃O₃ 
• 1373433-10-3 C₂₆H₂₅ClFN₃O₃S 
• 1373433-09-0 C₂₆H₂₅ClFN₃O₃S 
• 1373433-08-9 C₂₆H₂₅F₂N₃O₃S 
• 1373433-06-7 C₂₆H₂₅F₂N₃O₃S 
• 1373433-05-6 C₂₇H₂₉N₃O₄S 
• 1373433-04-5 C₂₇H₂₉N₃O₃S 
• 1373433-03-4 C₂₆H₂₆ClN₃O₃S 
• 1373433-02-3 C₂₆H₂₆FN₃O₃S 
• 1373433-01-2 C₂₆H₂₇N₃O₃S 
• 1373432-93-9 C₃₁H₃₇N₃O₃ 
• 1373432-92-8 C₂₈H₃₁N₃O₃ 
• 1373432-90-6 C₂₇H₂₈ClN₃O₃ 

Relevant articles and documents

Synthesis and SAR study of pyrrolo[3,4-b]pyridin-7(6H)-one derivatives as melanin concentrating hormone receptor 1 (MCH-R1) antagonists

The discovery and optimization of novel pyrrolo[3,4-b]pyridin-7(6H)-one MCH-R1 antagonists are described. A systematic SAR study probing the effects of aryl-, benzyl- and arylthio-substituents at the 2-position of the pyrrolo[3,4-b]pyridin-7(6H)-ones led to identification of the 2-[(4-fluorophenyl)thio] derivative 7b as a highly potent MCH-R1 antagonist. This compound also has favorable pharmacokinetic properties along with a high metabolic stability and a minimal impact on CYP isoforms and hERG.

NOVEL AMINO ALCOHOL-SUBSTITUTED ARYLTHIENOPYRIMIDINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS

The invention relates to amino alcohol-substituted arylthienopyrimidinones and their derivatives, and their physiologically tolerated salts and physiologically functional derivatives, their preparation, medicaments comprising at least one amino alcohol-su

BI-ARYL META-PYRIMIDINE INHIBITORS OF KINASES

The invention provides biaryl meta-pyrimidine compounds having the general structure (A). The pyrimidine compounds of the invention are capable of inhibiting kinases, such as members of the Jak kinase family, and various other specific receptor and non receptor kinases.