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Cyclopropanecarboxylic acid, 2-nitro, cis(8CI) is a chemical compound characterized by a cyclopropane ring, a carboxylic acid group, and a nitro group positioned in a cis configuration. This unique arrangement of functional groups endows the compound with specific stereochemical properties that influence its reactivity and biological activity. It is a promising candidate for the synthesis of pharmaceuticals and agrochemicals due to its distinctive structure and properties.

22882-44-6

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22882-44-6 Usage

Uses

Used in Pharmaceutical Industry:
Cyclopropanecarboxylic acid, 2-nitro, cis(8CI) is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and properties make it a valuable building block for the development of new drugs with novel therapeutic effects. Cyclopropanecarboxylic acid, 2-nitro-, cis(8CI)'s reactivity and stereochemistry can be exploited to create innovative drug candidates with improved efficacy and selectivity.
Used in Agrochemical Industry:
Cyclopropanecarboxylic acid, 2-nitro, cis(8CI) is also utilized in the synthesis of agrochemicals, particularly in the development of new pesticides. Its unique structure and properties can contribute to the creation of more effective and environmentally friendly pest control agents. Cyclopropanecarboxylic acid, 2-nitro-, cis(8CI)'s reactivity and stereochemistry can be harnessed to design pesticides with enhanced target specificity and reduced non-target effects.
However, it is important to note that Cyclopropanecarboxylic acid, 2-nitro, cis(8CI) should be handled and used with caution due to its potential toxic effects and environmental impact. Proper safety measures and responsible practices should be implemented to minimize any adverse consequences associated with its use.

Check Digit Verification of cas no

The CAS Registry Mumber 22882-44-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,8,8 and 2 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 22882-44:
(7*2)+(6*2)+(5*8)+(4*8)+(3*2)+(2*4)+(1*4)=116
116 % 10 = 6
So 22882-44-6 is a valid CAS Registry Number.

22882-44-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (1R,2S)-2-nitrocyclopropane-1-carboxylic acid

1.2 Other means of identification

Product number -
Other names Cyclopropanecarboxylicacid,2-nitro-,cis-(8CI)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:22882-44-6 SDS

22882-44-6Upstream product

22882-44-6Downstream Products

22882-44-6Relevant academic research and scientific papers

Multigram synthesis of trans -2-(trifluoromethyl)cyclopropanamine

Bezdudny, Andrii V.,Klukovsky, Denis,Simurova, Natalia,Mykhailiuk, Pavel K.,Shishkin, Oleg V.,Pustovit, Yurii M.

experimental part, p. 119 - 122 (2011/03/19)

2-(Trifluoromethyl)cyclopropanamine was synthesized. The key step of the synthesis is a transformation of the carboxy group into the trifluoromethyl group by using sulfur tetrafluoride. Twenty gram of the target product was conveniently prepared in a single batch. Georg Thieme Verlag Stuttgart · New York.

Synthesis of trans-(2-aminocyclopropyl)alanine - A key constituent of the novel antitumor antibiotic belactosin A

Brandl,Kozhushkov,Loscha,Kokoreva,Yufit,Howard,De Meijere

, p. 1741 - 1744 (2007/10/03)

Racemic 3-(trans-2-aminocyclopropyl)alanine was prepared in its 3,3-dideuterio-labelled form 3b from tert-butyl 2,3-dibromopropanoate 4 and nitromethane through a nine-step sequence in 8% overall yield. The newly developed access to enantiomerically pure (trans-2-nitrocyclopropyl)methanol (S,S)-6a also constitutes a formal synthesis of enantiomerically pure 3-(trans-2-aminocyclopropyl)alanine (S,S,S)-3a, a key intermediate for the total synthesis of the novel antitumor antibiotic belactosin A.

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