22884-29-3

Usage

Uses

Used in Organic Synthesis:
Isobutyltriphenylphosphonium bromide is used as a research intermediate for the synthesis of various organic compounds. Its unique structure and reactivity make it a versatile building block in the development of new molecules with potential applications in various fields.
Used in Pharmaceutical Industry:
Isobutyltriphenylphosphonium bromide is used as a key component in the synthesis of phosphonium salts with antiviral properties. These salts have shown promise in the development of new antiviral drugs, making Isobutyltriphenylphosphonium bromide an essential part of the pharmaceutical industry's efforts to combat viral infections.
Used in Antiviral Research:
In the field of antiviral research, Isobutyltriphenylphosphonium bromide is utilized as a starting material for the creation of phosphonium salts. These salts have demonstrated antiviral activity, making them potential candidates for the development of new antiviral medications to treat a wide range of viral diseases.
Used in Chemical Research:
Isobutyltriphenylphosphonium bromide is also employed in chemical research to study the properties and reactions of phosphonium salts. This knowledge can be applied to the design and synthesis of new compounds with specific applications in various industries, such as agriculture, materials science, and environmental science.

InChI:InChI=1/C22H24P.BrH/c1-19(2)18-23(20-12-6-3-7-13-20,21-14-8-4-9-15-21)22-16-10-5-11-17-22;/h3-17,19H,18H2,1-2H3;1H/q+1;/p-1

Upstream product

• 791-28-6 Triphenylphosphine oxide 
• 3878-45-3 triphenylphosphine sulfide 
• 78-77-3 Isobutyl bromide 
• 603-35-0 triphenylphosphine 

Downstream Products

• 112375-42-5 methyl (6Z)-8-methylnon-6-enoate 
• 112375-44-7 (Z)-methyl 6-methylhept-4-enoate 
• 112375-43-6 (Z)-methyl 9-methyldec-7-enoate 
• 90433-30-0 cis-3-Methyl-1-(m-cyanophenyl)-1-butene 
• 15325-61-8 3-methyl-1-phenyl-1-butene 
• 1091616-79-3 (3E)-1-ethyl-4,4-dimethyl-3-(2-methylpropylidene)cyclohexene 
• 1092699-17-6 (E)-(2-bromo-3-methylbut-1-enyl)benzene 
• 1092699-34-7 (E)-(2-iodo-3-methylbut-1-enyl)benzene 
• 1253394-27-2 4-trifluoromethyl-3-isopropyl-1-methyl-2-phenyl-1H-pyrrole 
• 1374645-90-5 (1R,4S,E)-1-isopropyl-4-methyl-2-(2-methylpropylidene)cyclohexane 
• 103786-20-5 (E)-1-methoxy-4-(3-methyl-but-1-en-1-yl)benzene 
• 103786-19-2 (Z)-1-methoxy-4-(3-methylbut-1-en-1-yl)benzene 

Relevant academic research and scientific papers

An Easy-to-Machine Electrochemical Flow Microreactor: Efficient Synthesis of Isoindolinone and Flow Functionalization

Flow electrochemistry is an efficient methodology to generate radical intermediates. An electrochemical flow microreactor has been designed and manufactured to improve the efficiency of electrochemical flow reactions. With this device only little or no supporting electrolytes are needed, making processes less costly and enabling easier purification. This is demonstrated by the facile synthesis of amidyl radicals used in intramolecular hydroaminations to produce isoindolinones. The combination with inline mass spectrometry facilitates a much easier combination of chemical steps in a single flow process.

New styrene derivative and method (by machine translation)

PROBLEM TO BE SOLVED: represented by chemical eq. (1), a copolymer of vinyl monomers used in the polymerization of styrene compound, and a manufacturing method thereof. SOLUTION: the styrene-based compound, and halogenated alkyl bistriphenylphosphine generates a reaction reagent Wittig, vinyl and the reagent Wittig nitrobenzaldehyde synthesized by reacting. ( In the formula, n is 0 or 1 and, R1 and R2 are, independently, a hydrogen atom, or, bisquaternary carbon number 3 or less, and, R1 and R2 of the total number of carbon atoms in the number of carbon atoms in 3 or more 5 or less. ) Selected drawing: no (by machine translation)

A convenient and mild chromatography-free method for the purification of the products of Wittig and Appel reactions

A mild method for the facile removal of phosphine oxide from the crude products of Wittig and Appel reactions is described. Work-up with oxalyl chloride to generate insoluble chlorophosphonium salt (CPS) yields phosphorus-free products for a wide variety of these reactions. The CPS product can be further converted into phosphine.

Pheromones, 89.- Wittig Syntheses of Alkyl-Branched and Cyclic Analogs of (Z)-5-Decenyl Acetate, the Sex Pheromone of Agrotis segetum (Lepitoptera: Noctuidae)

By means of (Z)-selective Wittig olefination alkyl-branched and cyclic analogs of (Z)-5-decenyl acetate, the sex pheromone of the turnip moth, Agrotis segetum (Lepidoptera: Noctuidae), have been synthesized. Key Words: Pheromones / (Z)-5-decenyl acetate / Wittig reactions / Agrotis segetum

Untersuchungen im Wittig-System nach einem ordnenden Konzept auf der Basis alternativer Prinzipien

Our results show that the stereoselectivity of the Wittig-reaction can be controlled by the variation of substituents in accord with the ORDERING CONCEPT OF ALTERNATIV PRINCIPLES (individual pairs, known and unknown classes of alternatives).The "all-phenyl Wittig-system" having three phenyl groups on phosphorous two in ylid- and aldehyd-position was chosen as a standard for our investigations.Differentiation in ylid-position and compensation on phosphorous and aldehyd-position were observed by the comparison of "patterns".Consequently, most of the selectivity rules of Wittig-reactions can be explained by the differentiation through alternatives in the ylid-position.Inversion or conservation of the "patterns" of measured data points to the variation in structure of starting materials, reaction rates and selectivities.Amount-controls were also described in certain systems.

The Stereocontrolled Horner-Wittig Reaction: Synthesis of Disubstituted Alkenes

Addition of the lithium derivatives of phosphine oxides Ph2P(O)CH2R1 to aldehydes gives erythro adducts (11) with good stereoselectivity.Reduction of α-diphenylphosphinoyl ketones (12) gives threo adducts (11) with even better stereoselectivity.Purification by flash chromatography and/or crystallisation followed by elimination of Ph2PO2 gives pure Z- or E-alkenes with high material conversion.Explanations are offered for the stereoselectivities, conditions defined for full stereochemical control, and guidelines suggested for approaches to a given alkene.