22900-17-0Relevant academic research and scientific papers
Formate formation during Co2(CO)8/PR3-catalyzed hydroformylation
Wood, Clayton D.,Garrou, Philip E.
, p. 170 - 174 (1984)
Careful examination of phosphine-modified cobalt hydroformylation (2000 psig, CO/H2 = 1:2, 190°C, Co/P = 1:1) as a function of PR3 reveals that moderate selectivity to formates can be achieved depending on the cone angle of the PR3 ligand chosen. These results are rationalized in terms of a stabilization or destabilization of a carboalkoxycobalt intermediate. Formate yields as high as 46% have been achieved with PEt3 at 4000 psig. The organometallic species present in the reaction are examined in detail for Co2(CO)8/PR3 (PR3 = PCy3, PEt3, and PPh3) by 31P NMR and IR spectroscopy.
