229020-91-1Relevant academic research and scientific papers
LIPOXYGENASE INHIBITORS
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Paragraph 00447-00448; 00450-00451, (2021/10/02)
Various embodiments of the present disclosure are directed to compounds having Formula (I), Formula (IA), Formula (IB), Formula (IC), Formula (ID), Formula (IE), and/or pharmaceutically acceptable salts thereof. The compounds can be suitable for inhibiting lipoxygenases, and/or treating associated diseases, such as Alzheimer's disease. In some embodiments, the compounds may be administered to a patient as part of a pharmaceutical formulation.
Facile one-pot synthesis of 6-monosubstituted and 6,12-disubstituted 5,11-dihydroindolo[3,2-b]carbazoles and preparation of various functionalized derivatives
Gu, Rong,Hameurlaine, Ahmed,Dehaen, Wim
, p. 7207 - 7213 (2008/02/11)
(Chemical Equation Presented) A facile three-stage, one-pot approach for the synthesis of a variety of novel 6-monosubstituted and 6,12-disubstituted 5,11-dihydroindolo[3,2-b]carbazoles, in moderate to good yields (20-50%), has been developed, based on th
Facile one-pot synthesis of novel 6-monosubstituted 5,11-dihydroindolo[3,2- b]carbazoles and preparation of different derivatives
Gu, Rong,Hameurlaine, Ahmed,Dehaen, Wim
, p. 1535 - 1538 (2007/10/03)
The synthesis of novel 6-monosubstituted 5,11-dihydroindolo[3,2-b] carbazoles was accomplished by a three-stage one-pot procedure involving condensation of indole and an aldehyde affording 3,3′-bis(indolyl) methanes, followed by isomerization to the 2,3′-
Syntheses of 6-substituted indolo[3,2-b]carbazoles, including 6- formylindolo[3,2-b]carbazole, an extremely efficient ligand for the TCDD (Ah) receptor
Tholander, Joakim,Bergman, Jan
, p. 6243 - 6260 (2007/10/03)
A number of 6-substituted indolo[3,2-b]carbazoles have been synthesized using 2,3-diindolylmethane 5 as a crucial precursor. Most notably, 6- formylindolo[3,2-b]carbazole 3 has been synthesized, and thereby a previously assigned structure has been confirmed. 6-Formylindolo[3,2-b]carbazole 3 is an extremely efficient ligand for the TCDD (Ah) receptor. A much improved synthesis of 2,3-diindolylmethane 5 has also been developed.
